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UOPX - NRP 507 Advanced Pharmacology - Final Exam Review 2024.

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  • August 14, 2024
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  • 2024/2025
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NRP 507



Advanced Pharmacology

FINAL EXAM REVIEW



2024

,1. Multiple Choice: Which of the following medications is considered a
first-line treatment for heart failure?

A. Captopril
B. Furosemide

C. Metoprolol

D. Digoxin

Correct Answer: C. Metoprolol

Rationale: Metoprolol is a beta-blocker that is commonly used as a first-
line treatment in heart failure due to its ability to reduce the heart rate and
decrease the workload on the heart.



2. Fill-in-the-Blank: ________ is the process by which a drug’s therapeutic
effects are diminished over time due to continuous use.

Correct Answer: Tachyphylaxis

Rationale: Tachyphylaxis refers to the rapid decrease in response to a
drug after repeated doses over a short period of time.



3. True/False: Glucocorticoids are recommended as a long-term treatment
option for asthma.

Correct Answer: False

, Rationale: While glucocorticoids are effective for controlling acute
exacerbations of asthma, they are not recommended for long-term
treatment due to potential side effects.



4. Multiple Response: Select all that apply. Which of the following are
potential adverse effects of aminoglycosides?

A. Ototoxicity

B. Nephrotoxicity

C. Hepatotoxicity

D. Cardiotoxicity

Correct Answers: A. Ototoxicity, B. Nephrotoxicity

Rationale: Aminoglycosides are known to cause ototoxicity and
nephrotoxicity, which are toxic effects on the ears and kidneys, respectively.



5. Multiple Choice: What is the mechanism of action of ACE inhibitors?

A. They block the conversion of angiotensin I to angiotensin II.

B. They increase the excretion of sodium and water.

C. They inhibit the sympathetic nervous system.
D. They cause vasodilation by blocking calcium channels.

Correct Answer: A. They block the conversion of angiotensin I to
angiotensin II.

Rationale: ACE inhibitors work by inhibiting the angiotensin-converting
enzyme, which is responsible for the conversion of angiotensin I to
angiotensin II, a potent vasoconstrictor.

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