NUR 254 CHAP 38 REVIEW QUESTIONS AND CORRECT ANSWERS
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Course
NUR 254
Institution
NUR 254
Allergy An inappropriate, often harmful response of the immune system to normally harmless substances Hypersensitive reaction to an allergen initiated by immunologic mechanisms that is usually mediated by IgE antibodies
Allergen the substance that causes the allergic response
Atopy refers to the ...
NUR 254 CHAP 38 REVIEW QUESTIONS
AND CORRECT ANSWERS
Allergy ✅An inappropriate, often harmful response of the immune system to normally
harmless substances
Hypersensitive reaction to an allergen initiated by immunologic mechanisms that is
usually mediated by IgE antibodies
Allergen ✅the substance that causes the allergic response
Atopy ✅refers to the allergic reactions characterized by IgE antibody action and a
genetic predisposition
Immunoglobulins and Allergic Response ✅Antibodies (IgE, IgD, IgG, IgM, and IgA)
react with specific effector cells and molecules and function to protect the body
IgE antibodies are involved in allergic disorders.
IgE molecules bind to an allergen and trigger mast cells or basophils.
These cells then release chemical mediators such as histamine, serotonin, kinins, SRS-
A, and neutrophil factor.
These chemical substances cause the reactions seen in allergic response.
Allergic Reaction ✅Allergen triggers the B cell to make IgE antibody, which attaches to
the mast cell. When that allergen reappears, it binds to the IgE and triggers the mast
cell to release its chemicals.
Chemical Mediators ✅Primary
Histamine
Eosinophil chemotactic factor of anaphylaxis
Platelet-activating factor
Prostaglandins
Secondary
Leukotrienes
Bradykinin
Serotonin
False
An antibody, not an antigen, is a protein substance developed by the body in response
to and interacting with a specific antigen, not antibody. ✅Is the following statement true
or false?
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