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NBME Combo with Rapid Fire NBME Path Study
and 7 others Latest Update 2024-2025 225 1800
Questions and 100% Verified Correct Answers
Actual Exam Guaranteed A+
Combo with "Rapid Fire NBME Path Study" and 7 others
"Hearld patch" that lead to "Christmas tree" rash in kids - CORRECT ANSWER:
pityriasis rosea
"itch-scratch" lesion on vulva that is white and scaly with hyperkeratosis - CORRECT
ANSWER: Lichen simplex chronicus
"pulseless disease" → thickening of arotic arch with increased ESR in young asian
females - CORRECT ANSWER: Takayasu's arteritis
"punched out" bone lesions with M-spike on electrophoresis, hypercalcemia, Ig in urine -
CORRECT ANSWER: Multiple Myeloma
↑ Estrogen with PTEN mutation - CORRECT ANSWER: Endometroid Adenocarcinoma
↓ Factor 8 - CORRECT ANSWER: Hemophilia A
↓ Factor 9 - CORRECT ANSWER: Hemophilia B
0157:H7 - CORRECT ANSWER: EHEC what is the the most common serotype
,1 and 139 - CORRECT ANSWER: Serogroups of V. cholerae that cause epidemic
cholera
12 hours after birth baby begins sucking frantically and crying inconsolably, also
overreacts to stimuli around him and has a marked startle response, symptoms resolve
in 2-3 weeks, what was the mother using - CORRECT ANSWER: heroin
16 - CORRECT ANSWER: HPV associated with squamous cell carcinoma
16, 18 - CORRECT ANSWER: HPVs targeted by Cervarix Vaccine
18 - CORRECT ANSWER: HPV associated with Cervical Adenocarcinoma
200 - CORRECT ANSWER: CD4 counts below this = progression to Aids
21 day old child presents with a firm mass on one side of the neck, and prefers to only
hold his head in one direction. Diagnosis? - CORRECT ANSWER: Congenital torticollis,
caused by malposition in utero.
22q11 heart defects - CORRECT ANSWER: Truncus or Tetralogy
30 yo with recurrent infections, diarrhea, pneumonia, and inflammatory bowel -
CORRECT ANSWER: Common variable Immunodeficiency (either T or B cells affected)
6,11 - CORRECT ANSWER: HPV associated with Condyloma Acuminata
60 yo patient with smudge cells in blood or lymphnodes - CORRECT ANSWER:
CLL/SLL
A 3 year old male presents with an H. influezae infection. What does this mean about
the patient, if the patient were vaccinated? - CORRECT ANSWER: He has been
infected with a non-capsular forming strain of H. flu
A baby is born with underdeveloped sacrum and lumbar region. There is urinary
incontinence and lower extremity paralysis. What is this, and what was the cause? -
CORRECT ANSWER: Caudal regression syndrome, caused by uncontrolled maternal
diabetes
A biopsy of a patient's collagen reveals large amounts of disulfide domains. What is
impaired in this patient? - CORRECT ANSWER: Extracellular protein cleavage,
removing the disulfide bonds
A breast biopsy shows pleomorphic high grade cells with central necrosis. Diagnosis? -
CORRECT ANSWER: Comedocarcinoma
A child has a deficiency in tetrahydrobiopterin synthesis. What neurotransmitters are
deficient? - CORRECT ANSWER: Tyrosine (amino acid), dopa, and serotonin. BH4 acts
as a cofactor in their synthesis
, A child has a heart defect and limited lower extremity exercise tolerance. Diagnosis? -
CORRECT ANSWER: Coarctation of the aorta
A child has cyanosis restricted to the lower body. What is the most likely cause if you
know he has a heart defect? - CORRECT ANSWER: Patent ductus arteriosus--due to
reversal of flow
A child has ulcerative lesions with intranuclear inclusions on the oral mucosa.
Diagnosis? - CORRECT ANSWER: HSV infection.
A child presents with retardation, eczema, and a mousy/musty body odor. Diagnosis? -
CORRECT ANSWER: Phenylketouria--phenylalanine hydroxylase genetic defect
(autosomal recessive)
A disorder has varied severity among family members, due to differential amounts of
inherited, mutated mitochondrial DNA within each cell. What is this called? - CORRECT
ANSWER: Heteroplasmy
A female has a long history of pruritis and fatigue. She has recently developed pale
stool and xanthelasma. What will be shown upon liver biopsy? - CORRECT ANSWER:
Lymphocytic infiltrate and destruction of interlobular bile ducts, characteristic of primary
biliary cirrhosis.
A female has persistent infections, bleeding, and immature lymphoid cells with auer
rods on blood smear. Diagnosis? - CORRECT ANSWER: Acute promyelocytic leukemia
(APL, M3 AML), due to t(15,17)
A gram positive bacteria contains metachromatic granules that stain for aniline dyes.
Most likely culprit? - CORRECT ANSWER: Corynebacteria diptheriae--staining for
methylene blue
A lesion of what cortical tract would cause resistance to passive flexion of the arm? -
CORRECT ANSWER: Spastic rigidity can be caused by any UMN lesion, including the
internal capsule, motor cortex, and the corticospinal tract
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