Pharmacology Exam 2 week 7
change in distribution of ions - ✔✔action potential
make electrical impulses which trigger myocardial contraction - ✔✔movement of cells
across membrane do what
PQRST - ✔✔5 phases of electrical current through muscular tissue
dysrhythmias: abnormal heart rhythm
Arrhythmia: no rhythm - ✔✔Dysrhythmias/Arrhythmias
originate above the ventricle - ✔✔Superventricular dysrrhythmia
lethal rhythms - ✔✔Ventricular dysrhythmias
block channels
%
block electrolyte flow through ion channels (conduction) or alter autonomic activity
(automaticity)
Grouped according to what stage of AP they affect (4 classes) - ✔✔Purpose of
antidysrhythmics
how are they grouped?
known allergies, 2nd or 3rd degree AV block - ✔✔Antidysrhythmics contraindications
N & V, diarrhea, dizziness, headache, QT prolongation - ✔✔Antidysrhythmics
common adverse reactions
pharm: sodium channel blocker
Action: blocks sodium ion channels in myocardial cells
Adverse: blood disorders, significant lupus syndrome, n &v, torsades
Contraindications: don't want to use with heart block and hypersensitivity -
✔✔Procainamide (Pronestyl)
, STUVIA
sodium channel blocker
Action: raises ventricular filbrillation threshold
adverse effects: resp distress, hypotension, confusion
contraindications: DPW, slough adams syndrome, severe AV and SA block -
✔✔Lidocaine (Xylocaine)
Potassium channel blocker
One of the best meds for controlling supraventricular and ventricular dysrhythmias
Action: prolong action potential duration and refractory period in cardiac tissues
Very bad long term effects: start turning blue/ purple which is permanent
interactions: warfarin - ✔✔Amiodarone (Cardarone, Pacerone)
moa
used for
long term affects
interactions
%
blocks calciuim slowing down cardiac conduction time
dramatic affects on av where it primarily works
Used for hypertrophic cardiac myopathy - ✔✔Verapril (Verelan, Calan)
moa
where it most affects
used for
prevent clots from happening again or growing - ✔✔Anticoagulation
stoppage of bleeding - ✔✔hemostasis
blood clot - ✔✔thrombosis
the sudden blockage of a blood vessel by an embolus
thrombis moving through blood vessel - ✔✔embolism
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