STUVIA 2024/2025
Chapter 43: Antiulcer Drugs
A patient who has been instructed to use a liquid antacid medication to treat gastrointestinal upset
asks the nurse about how to take this medication. What information will the nurse include when
teaching this patient?
a. Take a laxative if constipation occurs.
b. Take 60 minutes after meals and at bedtime.
c. Take with at least 8 ounces of water to improve absorption.
d. Take with milk to improve effectiveness. - ✔✔ANS: B
Since maximum acid secretion occurs after eating and at bedtime, antacids should be taken 1 to 3
hours after eating and at bedtime. Taking antacids with meals slows gastric emptying time and
causes increased gastrointestinal (GI) secretions. Patients should not self-treat constipation or
diarrhea. Patients should use 2 to 4 ounces of water when taking to ensure that the drug enters the
stomach; more than that will increase gastric emptying time. If possible, antacids should not be taken
with milk or foods high in vitamin D.
A patient who has symptoms of peptic ulcer disease will undergo a test that requires drinking a liquid
containing 13C urea and breathing into a container. The nurse will explain to the patient that this test
is performed to
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a. assess the level of hydrochloric acid.
b. detect H. pylori antibodies.
c. measure the pH of gastric secretions.
d. test for the presence of H. pylori. - ✔✔ANS: D
When H. pylori is suspected, a noninvasive test is performed by administering 13C urea, which, in the
presence of H. pylori, will release 13CO2. The test does not measure the amount of HCl acid or the
pH and does not detect H. pylori antibodies.
A patient is taking rabeprazole (Aciphex) 20 mg per day to treat a duodenal ulcer. After 10 days of
treatment, the patient reports that the pain has subsided. The nurse will counsel the patient to:
a. continue the medication for up to 4-8 total weeks of treatment.
b. reduce the medication dose by half.
c. stop taking the medication.
d. take the medication every other day. - ✔✔ANS: A
With treatment, ulcer pain may subside earlier, but the healing process may take 1 to 2 months.
Patients should be counseled to take the drug for the length of time prescribed. Reducing the dose or
taking less frequently is not recommended.
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, STUVIA 2024/2025
A patient with a peptic ulcer has been diagnosed with H. pylori. The provider has ordered
lansoprazole (Prevacid), clarithromycin (Biaxin), and metronidazole (Flagyl). The patient asks the
nurse why two antibiotics are needed. The nurse will explain that two antibiotics
a. allow for less toxic dosing.
b. combat bacterial resistance.
c. have synergistic effects.
d. improve acid suppression. - ✔✔ANS: B
The use of two antibiotics when treating H. pylori peptic ulcer disease helps to combat bacterial
resistance because H. pylori develops resistance rapidly. Giving two antibiotics, in this case, is not to
reduce the dose or to cause synergistic effects. Antibiotics do not affect acid production.
A patient who takes propantheline bromine (Pro-Banthine) and omeprazole (Prilosec) for an ulcer will
begin taking an antacid. The nurse will give which instruction to the patient regarding how to take the
antacid?
a. Take the antacid 2 hours after taking the propantheline.
b. Take the antacid along with a meal.
c. Take the antacid with milk.
d. Take the antacid with the propantheline bromine. - ✔✔ANS: A
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Antacids can slow the absorption of anticholinergics and should be taken 2 hours after anticholinergic
administration. Antacids should be given 1 to 3 hours after a meal and should not be given with dairy
products.
Which antacid is most likely to cause acid rebound?
a. Aluminum hydroxide
b. Calcium carbonate
c. Magnesium hydroxide
d. Magnesium trisilicate - ✔✔ANS: B
While calcium carbonate is most effective among the listed antacids in neutralizing acid, a significant
amount can be systemically absorbed and can cause acid rebound. The other antacids do not have
significant systemic absorption.
An elderly patient reports using Maalox frequently to treat acid reflux. The nurse should notify the
patient's provider to request an order for which laboratory tests?
a. Liver enzymes and serum calcium
b. Liver enzymes and serum magnesium
c. Renal function tests and serum calcium
d. Renal function tests and serum magnesium - ✔✔ANS: D
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