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GMS6504 Review Exam 1 Problem Set 1: Intro, Receptors, and Response Questions With Complete Solutions $10.99   Add to cart

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GMS6504 Review Exam 1 Problem Set 1: Intro, Receptors, and Response Questions With Complete Solutions

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GMS6504 Review Exam 1 Problem Set 1: Intro, Receptors, and Response Questions With Complete Solutions

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  • August 12, 2024
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  • 2024/2025
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  • Questions & answers
  • GMS6504
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GMS6504 Review Exam 1 Problem Set 1: Intro, Receptors,
and Response Questions With Complete Solutions


Which of the following would best be described as a system
independent parameter determining pharmacological response?

The number of receptors present
The cellular cascade
Pharmacokinetics
Receptor affinity for the ligand
Presence of an antagonist
Receptor affinity for the ligand
When taking a natural agonist and converting it to an antagonist
using synthetic chemistry, what are the desired effects on
affinity and efficacy?

Both increase
Both decrease
Affinity increases, efficacy decreases
Affinity decreases, efficacy increases
Affinity increases, efficacy decreases
In the Langmuir equation, which variable represents the
proportion of receptors that are bound by ligand?

, r
D
Kd
Rt
DR
r
If a ligand has an intrinsic activity, α, of 0.54, this ligand is best
considered a ______.

full agonist
partial agonist
antagonist
inverse agonist
partial agonist
If you do a cell culture experiment where you exogenously
express a receptor in cells, which variable in the equation R =
f(α •r • Rt) are you most directly controlling?
R
f
α
r
Rt
Rt

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