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Lehne-s Pharmacology CH 69 questions with answers
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Lehne-s Pharmacology CH 69 questions with answers
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Lehne's Pharmacology CH 69 questions withanswers
immunosuppressants - ANSWER: ➡ used to prevent organ rejection in allograft recipientsm m mm m m m m m m m m
mand to treat autoimmune disorders (rheumatoid arthritis)
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life - ANSWER: ➡ Allograft recipients must take immunosuppressants for:
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infection and lymphomas - ANSWER: ➡ Immunosuppressants increase the risk of:
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cyclosporine and tacrolimus - ANSWER: ➡ are the most effective immunosuppressant
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available
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used primarily in allograft recipients
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cyclosporine - ANSWER: ➡ causes kidney injury in up to 75% of patients
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other nephrotoxic drugs, including amphotericin B, aminoglycosides, and NSAIDS -
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ANSWER: ➡ Kidney damage from cyclosporine can be intensified by:
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inhibit - ANSWER: ➡ Drugs that _____ CYP3A4 can increase cyclosporine
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induce - ANSWER: ➡ Drugs that ______ CYP3A4 can decrease cyclosporine
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grapefruit juice - ANSWER: ➡ inhibits cyclosporine metabolism, and can thereby greatly
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increase cyclosporine levels
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