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CMV and EBV: Key Terms and Concepts Exam Practice Questions and Answers (100% Verified)
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CMV and EBV: Key Terms and Concepts Exam Practice Questions and Answers (100% Verified)
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©PREP4EXAMS @2024 [REAL EXAM DUMPS] Tuesday, July 16, 2024 7:36 PMCMV and EBV: Key Terms and Concepts Exam Practice
Questions and Answers (100% Verified)
endemic - ✔️✔️(adj.) native or confined to a particular region or people; characteristic of or
prevalent in a field
Prevalence - ✔️✔️The number or proportion of cases of a particular disease or condition
present in a population at a given time.
allograft - ✔️✔️transplantation of healthy tissue from one person to another person; also called
homograft
Cytomegalovirus (CMV) - ✔️✔️DNA virus that accounts for many respiratory, ophthalmic,
and liver infections
Cytomegalic inclusion disease (CID) - ✔️✔️Transmitted across the placenta; causes nervous
system damage (cognitive disabilities) or hearing loss in newborns-can be fatal
Prevalence of CMV - ✔️✔️Endemic worldwide, prevalence (seropositivity) increases with age
How is CMV transmitted? - ✔️✔️Oral, respiratory and sexual. Transfusion in white blood cells
or tissues, breast milk-post natal infection, transplacental
What is are the characteristics of CMV? - ✔️✔️Enveloped virus (close contact), DNA virus
Latent CMV Infection - ✔️✔️Genetic material remains in cells without being expressed. No
signs or symptoms of disease.
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, ©PREP4EXAMS @2024 [REAL EXAM DUMPS] Tuesday, July 16, 2024 7:36 PM
How does reactivation of latent infection in CMV occur? - ✔️✔️Allograft transplant one's own
strain of CMV can be reactivated by receiving tissue from another seropositive donor.
What are the signs and symptoms of acquired CMV infection? - ✔️✔️Most are asymptomatic.
When symptoms do occur they appear as sore throat fever swollen glands, chills, aches and
pains. Mononucleosis like. Immunocompromised patients can face life-threatening
disseminated severe infection.
CMV antibodies - ✔️✔️Immunocompetent do seroconvert
CMV does not result in the production of heterophile antibodies
Primary Transfusion Associated CMV characteristics are - ✔️✔️A seronegative recipient
received components from an active or latent donor
Virus is found in the blood and urine
May be symptomatic or asymptomatic
Reactivated Transfusion Associated CMV characteristics are - ✔️✔️Seropositive recipient
receives antibody positive or negative donor
An allograft reaction of receiving the transfusion that reactivates the recipient
Mostly asymptomatic
Reinfection Transfusion Associated CMV characteristics are - ✔️✔️Strain of the donor is
different than the recipients strain (in otherwords, both are seropositive to begin with).
Significant antibody response due to exposure to a new strain, and viral shedding.
Congenital CMV - ✔️✔️The most common eye-related complication of congenital CMV
infection is chorioretinitis.
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