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APEA- Endocrine Patho

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APEA- Endocrine Patho Which diagnosis is associated with T cell-mediated destruction of beta cells in the pancreas? Diabetes insipidus Type 1 diabetes mellitus Type 2 diabetes mellitus Gestational diabetes - ANSWER-Type 1 diabetes mellitus In thyrotoxic crisis, T3 and T4 are overproduce...

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  • August 12, 2024
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  • 2024/2025
  • Exam (elaborations)
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  • APEA- En
  • APEA- En
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APEA- Endocrine Patho




Which diagnosis is associated with T cell-mediated destruction of beta cells in the pancreas?

Diabetes insipidus

Type 1 diabetes mellitus

Type 2 diabetes mellitus

Gestational diabetes - ANSWER-Type 1 diabetes mellitus



In thyrotoxic crisis, T3 and T4 are overproduced, causing hypermetabolism from the overproduction of:



dopamine.

catecholamines.

epinephrine.

norepinephrine. - ANSWER-epinephrine



In thyrotoxic crisis (also known as thyroid storm), the thyroid gland secretes the thyroid hormones
triiodothyronine (T3) and/or thyroxine (T4). When T3 and/or T4 are overproduced, systemic adrenergic
activity increases. The result is epinephrine overproduction and severe hypermetabolism, leading rapidly
to cardiac, GI, and sympathetic nervous system decompensation.

, Patients with Graves disease may experience comorbid diseases including:

peptic ulcer disease.

iron deficiency anemia.

lupus erythematosus.

thyroid cancer. - ANSWER-lupus erythematosus



Increased risk for multiple autoimmune conditions



Hypofunction of the adrenal cortex that results in an inadequate release of glucocorticoids is:



Sprue syndrome.

Cushing syndrome.

Addison's disease.

hypoparathyroidism. - ANSWER-Addison's disease



Addison's disease results from inadequate production of cortisol.



Diabetes is the leading cause of:

urosepsis.

end-stage renal disease.

acute coronary syndrome.

pancreatitis. - ANSWER-end-stage renal disease



Diabetes is a leading cause of end-stage renal disease, adult-onset blindness, and nontraumatic lower
extremity amputations in the United States. The chronic hyperglycemia that is associated with diabetes
mellitus and a dysregulated metabolic system may be associated with secondary damage in multiple
organ systems, especially the kidneys, eyes, nerves, and blood vessels.



An autoimmune disorder characterized by abnormal stimulation of the thyroid gland by antibodies that
act through normal TSH receptors is:

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