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GMS 6551 Drug Studies Questions With Complete Solutions
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GMS 6551 Drug Studies Questions With Complete Solutions
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GMS 6551 Drug Studies Questions With Complete SolutionsDrug targets Correct Answers - enzymes
...... ......
- receptors
- proteins
- DNA
- RNA
- carbohydrates
- lipids
Bacterial enzymes Correct Answers - easier to target than human
...... ......
proteins
In vitro Correct Answers - fast
...... .... ..
- cheap
- test tube
In vivo Correct Answers - complex
...... .... ..
- expensive
- may mask things seen in test tube
- harmful to animals
Lead compound Correct Answers - first compound that has
...... ... ...
deisred activity
SAR Correct Answers - structure activity relationships
...... ......
- optimize lead compounds
- makes drug better
- elimation of unneeded effects
Pharmacokinetics Correct Answers - dose given & how often
...... ......
, - absorption
- distribution
- metabolism
- excretion
- determined in vitro or in vivo
Pharmacodynamics Correct Answers - what drug does to the
...... ......
body
- MOA
- potentcy
- efficacy
- toxicity
Pharmacogenetics Correct Answers - how genetic makup
...... ......
impacts drug function
Pharmacotherapeutics Correct Answers - how drugs are
...... ......
clinically used
Main targets Correct Answers - receptors
...... ......
- enzymes
Drug classification Correct Answers - chemical properties
...... ......
(benzos)
- MOA (ACEI)
- disease or condition used to treat (analgesics)
- abuse potential
1) OTC
2) Prescription
3) Orphan drugs
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