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GMS 6551:3 Pharmacodynamics Questions With Complete Solutions
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GMS 6551:3 Pharmacodynamics Questions With Complete Solutions
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GMS 6551:3 Pharmacodynamics Questions With CompleteSolutions
The most common target of drugs is
enzymes
hormones
receptors
ion channels
DNA Correct Answers receptors
... ... ......
Gleevec targets
enzymes
hormones
RNA
ion channels
DNA Correct Answers enzymes
... ... ......
A diabetic receives an injection of insulin. Once the insulin
reaches the pancreas, how long do you expect it to take before a
response can be measured?
Milliseconds
Seconds
Minutes
Hours
Days Correct Answers Minutes
...... ......
, A dose of agonist occupies 30% of receptors and gives an effect
of 50. According the occupancy theory, what effect would you
expect from a dose that occupies 90% of receptors?
17
50
90
150
Cannot predict Correct Answers 150
...... ......
Naloxone binds to the opioid receptor, preventing opioids from
binding, therefore preventing an effect. In this situation,
naloxone is a(n) ______ and the opioid is a(n) ______.
agonist; agonist
agonist; antagonist
antagonist; agonist
antagonist; antagonist Correct Answers antagonist; agonist
...... ......
Most drugs bind in such a way that it is reversible without a
chemical reaction. These drugs must therefore lack which type
of bond with their targets?
Covalent
van der Waals
Hydrogen
Hydrophobic Correct Answers Covalent
...... ......
Drug A requires 15 µM to reach 50% of its maximum response
while Drug B requires 50 µM to reach 50% of its maximum
response. Which drug is more potent?
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