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Pharmacology Module -1,-2 & -3 EXAM REVIEW, pharmacology module 3, Adv Pharm 5334 UTA Exam Test Bank $13.49   Add to cart

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Pharmacology Module -1,-2 & -3 EXAM REVIEW, pharmacology module 3, Adv Pharm 5334 UTA Exam Test Bank

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  • NURS 5334
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Pharmacology Module -1,-2 & -3 EXAM REVIEW, pharmacology module 3, Adv Pharm 5334 UTA Exam Test Bank

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  • August 10, 2024
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  • 2024/2025
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  • NURS 5334
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Pharmacology Module #1,#2 &
#3 EXAM REVIEW, pharmacology
module 3, Adv Pharm 5334 UTA
Exam 1 Questions and Complete
Solutions Graded A+

Denning [Date] [Course title]

,What are the four phases of pharmacokinetics? - Answer: - Absorption, distribution, metabolism,
excretion



Bioavailability - Answer: The extent of drug that becomes available to the body after absorption



"Free Drug" - Answer: - The drug that is not bound to protein that is free to exert a therapeutic effect



Nicotine is a? What (3) effects does it have? - Answer: - A CYP 450 inducer

- Increase metabolism of drug and result in decreased effects and shortened half-life



Grapefruit Juice is a? What (3) effects does it have? - Answer: - A CYP 450 Inhibitor

- Decreased metabolism

- Drug toxicity

- Shorted half life



Kidneys - Answer: The main organs responsible for drug excretion



Half-life - Answer: The time required for one half of the drug to be removed from the body



Peak Effect - Answer: The time taken for the drug to reach maximum therapeutic response



Peak Level - Answer: - The highest concentration of drug in blood



Drug Polymorphism - Answer: The effect of a patient's age, gender, size, body composition and other
characteristics on the pharmacokinetics of a specific drug



Drug Polymorphism can be categorized into what (3) different factors. - Answer: 1. Environmental (diet
& nutritional status)

2. Cultural

3. Genetic factors

,How can high-fat diets affect absorption? How can malnutrition affect absorption? - Answer: - High Fat
Diets = increased absorption of many drugs



- Malnutrition = alter the ability to absorb or eliminate medication



Drugs like Heroin and LSD are considered category ____? - Answer: - Category I



The normal range for albumin is _____ - _____ grams/dL - Answer: - 4-6 grams/dl



If the gastric pH level is high, this means the stomach is more _______ than normal. - Answer: - Alkaline



Prodrug - Answer: - A drug that is converted from an inactive form into an active metabolite through
biotransformation in the liver



Paradoxical Reaction - Answer: - The opposite reaction than what is expected with the specific drug



The three names for Medications? - Answer: - Chemical, trade and generic



Chemical name of a drug refers to? - Answer: - The chemical structure



Trade name / brand name of a medication - Answer: - proprietary name

- more expensive than generic

- Shorter, easier name



Generic Medication - Answer: - Most commonly used

- most prescriptions are



Pharmacokinetics of Oral Medications (4 steps) - Answer: 1. Drug is ingested

, 2. Disintegrated

3. Forms a dissolution

4. Absorption can occur



What is absorption? - Answer: - The movement of a drug from its site of administration into the
bloodstream for distributions to tissues



A drug that is absorbed through the intestines must ______ pass through the _______ before it reaches
the ________ circulation. - Answer: - A drug that is absorbed through the intestines must first pass
through the liver before it reaches the systemic circulation



High first-pass effect - Answer: - A large portion is changed into an inactive metabolite



Which routes of medication administration would be impacted by first pass effect? - Answer: - Anything
GI related can have first pass effect

- Oral and Rectal administration



Which routes will not be impacted by first-pass effect? - Answer: - Parenteral and topical



What are the (3) basic routes of medication administration? - Answer: - Enteral, Parenteral, and topical



What is enteral route of medication administration? - Answer: - Is absorbed through the GI mucosa



What is parenteral route of medication administration? What does it normally refer to? - Answer: - The
fastest route

- Any route other than the GI tract

- Normally refers to injection

-



Would the dose of medication for an oral tablet be the same as intravenous injection of the same
medication? Why or Why Not? Which will have a larger dose? - Answer: - No

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