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6521N - Advanced Pharmacology midterm Exam Questions and Complete Solutions
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6521N - Advanced Pharmacology midterm Exam Questions and Complete Solutions
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6521N - AdvancedPharmacology midterm Exam
Questions and Complete
Solutions
Denning Muriithi [Date] [Course title]
, 6521N - Advanced Pharmacology midterm
1. What are the two components of prescriptive authorityAnswer: The right
to prescribe independently
And the right to prescribewithout limitation
2. The regulation for prescriptive Authority comes fromAnswer: The
State Board of Nursing
The State Board of
Medicine State Board of
Pharmacy
3. What is the most importantfunction to evaluate when prescribing a
medica- tionAnswer: Hepatic and renal function
4. What must you pay attention to when performing a refillAnswer: 1. Is
this a newer medication for a patient
2. changing the dose of frequency
3. am I adding new medicines to their regimen
4. is this patient having undesired effects
5. How long has it been since I've seen the patient
6. Is this a Schedule II medication
*If the answer to any of these questions is yes consider a shorter time
period for a refill (one to three months)
5. What should be included in the teaching for drug monitoringAnswer:
What test is needed
When is test required
Where will testing take
place Why is testing
necessary
How does the patient prepare for testing
6. What periodic Laboratory Testing is needed with Ace and ARBAnswer:
Potassium/ creatinine
These drugs can cause hyperkalemia
Renal perfusion is dependent on Angiotensin in some patients increased
creatinine may require a change in medication
7. What LaboratoryTesting is required with amiodaroneAnswer: Liver
function, thyroid function, pulmonary function and chest x-rays
Hepatoxicity is an adverse effect
Either hypo or hyperthyroidism may occur
Pulmonary toxicity is not uncommon, affects maybe permanent
8. What Laboratory Testing is required with anticonvulsantsAnswer: Serum
drug lev- els-some have a very narrow therapeutic index
9. What Laboratory Testing is required with lithiumAnswer: CBC, lithium
, 6521N - Advanced Pharmacology midterm
level, thyroid function, renal function, serum electrolytes
, 6521N - Advanced Pharmacology midterm
This drug has a narrow therapeutic
margin, lithium can cause leukocyte
elevation
Both hypo and hyperthyroidism may
occur Renal damage is a serious
adverse effect
Nephrogenic diabetes insipidus May occur, and hyponatremia can
create complica- tions
10.What are the four basic pharmacokinetic processesAnswer: absorption,
distribution, metabolism, excretion
11.What is the combination of metabolism and excretion calledAnswer:
Elimination
12.What determines the concentration of a drug at its site of actionAnswer:
The four pharmacokinetic processes acting in concert
13.What are the three ways for drugs to cross the cell membraneAnswer:
Passage through channels or pores
Passage with the aid of a transport
system Direct penetration of the
membrane
Of all three direct penetration of the membrane is most common
14. What is an example of a drug that can pass through a Channel or
poorAnswer: -
Sodium or potassium
15.What are common drug transportersAnswer: Pgp- P - glycoprotein
16.What is the general rule in chemistryAnswer: dissolve like Membranes
are composed primarily of lipids-therefore to directly penetrate
membranes a drug must be lipid soluble or lipophilic
17.What is a kind of moleculethat is not lipid soluble and therefore
cannot penetrate membranesAnswer: Polar molecules and ions
18.What is a polar molecule?Answer: a molecule in which the charges
are unevenly distributed
Example is water
19.What are ionsAnswer: Charged particles that have a net
electrical charge determined by the pH of the surrounding
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