NSG 318 Exam 1 Practice Questions and Correct Answers
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Course
NSG 318
Institution
NSG 318
Pharmacokinetics The process of drug movement throughout the body that is necessary to achieve drug action
› Pharmacodynamics The study of the effects of drugs on the body
Pharmacogenetics The study of genetic factors that influence an individual's response to a specific drug
› 6 Rights of M...
NSG 318 Exam 1 Practice Questions and
Correct Answers
Pharmacokinetics ✅The process of drug movement throughout the body that is
necessary
to achieve drug action
› Pharmacodynamics ✅The study of the effects of drugs on the body
Pharmacogenetics ✅The study of genetic factors that influence an individual's
response to
a specific drug
› 6 Rights of Medication Safety ✅Right patient
- Right drug
- Right dose
- Right route
- Right time
- Right documentation
Chemical Name ✅- Describes the chemical structure of the drug
› N-aceTYL-p-aminopheno
› Generic Name ✅Official, nonproprietary name
Brand (Trade) Name ✅Proprietary name
Generic Drugs ✅› Must be approved by the FDA
› Same active ingredients as brand-name drug
› Usually less expensive
› May contain products that aid in providing the shape of the
tablets, control the timing of release in the body
› Health care provider must state on prescription whether a
generic drug can be substituted for the brand name drug
Over-the -Counter (OTC) Drugs ✅Drugs that have been found safe and appropriate for
use
without the direct supervision of a health care provider
› Important for the nurse to be aware of their clients use of OTC
drugs
Beneficence ✅the duty to protect research subjects from harm. It involves assessing
potential risks and possible benefits and ensuring the benefits are greater than the risk.
, Risk-Benefit Ratio
absorption ✅the movement of the drug into the bloodstream after administration
excipients ✅Fillers and inert substances—such as simple syrup, vegetable gums,
aromatic powder, honey, and various elixirs
used in drug preparation to allow the drug to take on a particular size and shape and to
enhance drug dissolution
Enteric-coated (EC) drugs ✅resist disintegration in the gastric acid of the stomach
should not be crushed because crushing alters the place and time of absorption of the
drug
sustained-release (beaded) capsules ✅should not be crushed
Bioavailability ✅the percentage of administered drug available for activity
orally administered drugs, bioavailability is affected by absorption and first-pass
metabolism
Factors that alter bioavailability ✅e(1) drug form, such as tablet, capsule, sustained-
release beads, liquid, transdermal patch, suppository, or inhalation;
(2) route of administration (e.g., enteral, topical, or parenteral);
(3) gastric mucosa and motility;
(4) administration with food and other drugs; and
(5) changes in liver metabolism caused by liver dysfunction or inadequate hepatic blood
flow
Distribution ✅the movement of the drug from the circulation to body tissues.
protein binding ✅The portion of the drug bound to protein is inactive because it is not
available to interact with tissue receptors and therefore is unable to exert a
pharmacologic effect
Free drugs ✅are able to exit blood vessels and reach their site of action, causing a
pharmacologic response
Metabolism (biotransformation) ✅process by which the body chemically changes
drugs into a form that can be excreted
primary site of metabolism ✅liver
half-life ✅time it takes for the amount of drug in the body to be reduced by half
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