pathology for the health professions test 2 Questions And Answers
8 views 0 purchase
Course
Pathology
Institution
Pathology
Explain the pathogenesis of common local symptoms of neoplasia.
~ Local symptoms of neoplasia are often related to compression or
obstruction of normal tissue (e.g.,bronchial obstruction and coughing in a
patient with lung cancer) or are related to erosion and destruction of normal
tissue ...
pathology for the health
professions test 2 Questions
And Answers
what is the main difference between innate and acquired immunity?
✓~ acquired immunity- a pathogen specific and requires previous antigen
exposure and primarily mediated by B AND T lymphocytes
natural immunity-does not require pervious antigen exposure and mediated
primarily by segmented neutrophils
what are the main difference between T AND B lymphocytes and between CD4+
AND CD8+ lymphocytes?
✓~ T lymphocytes undergo selection and maturation in the thymus.
B lymphocytes produce antigen -specific proteins that are secreted into the
blood
cd4- are helper T-lymphoctyes
cd8-are killer t-lymphocytes they kill foreign and virally infected cells
,what are the most important common features and functions of immunoglobulin
?
✓~ IgG-efficient at activating complement and targeting pathogens for
phagocytosis
IgM-Provide 1st line of defense against bacterial polysaccharides
IgA- found in saliva tears and bodily secretions
IgD- cell membrane associated and serves a receptor for early B-cell activation
IgE- antibodies are bound to the surface of mast cells, providing an antigen-
specific receptor for mast cell activation and degranulation
what is the role of the major histocompatibility complex and cytokines in the
response to foreign antigens?
✓~ MHC-a gene cluster that encodes cell-surface glycoproteins
cytokines-regulate the activity of other effector cells through complex
paracrine signaling mechanisms
what is the mechanism of type 1 hypersensitivity?
, ✓~ reflects mast cell degranulation with the release of histamine and
other vasoactive mediation of acute inflammation
what does type 1 hypersensitivity requires?
✓~ pervious exposure to a pathogen, which results in the generation of
IgE antibody
what are the two basic mechanisms of type 2 hypersensitivity?
✓~ 1- complement-mediated tissue hemolysis and or damage
2-antibody dependent cellular cytotoxicity(ADCC)
Which diseases are caused by type 2 hypersensitivity reaction?
✓~ -graves disease
-myasthenia gravis
-goodpasture syndrome
Which diseases are caused by type 3 hypersensitivity reaction?
✓~ -systemic lupus erythematosus
-polyarteritis nodosas
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller Latestupdate. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $11.49. You're not tied to anything after your purchase.
