Treatment to increase sex drive
~ Hormone therapy. Androgens increase the sex drive in women and men with
low testosterone concentrations. Women may experience virilizing effects, some of
which are irreversible (e.g., deepening of the voice). In men, prolonged use of
androgens produces hyp...
High risk for weight gain and metabolic abnormalities.
Olanzapine (Zyprexa)
✓~ "Pine" SGA
FDA approved for treatment in those age 13 and older.
Best tolerated antipsychotic, but high metabolic risk.
Highest risk for weight gain, blood dyscrasias, QT prolongation, CVD, cerebrovascular
effects, hyperglycemia, and hyperprolactinemia.
Requires up to 30% dosage increase for patients who smoke.
Quetiapine (Seroquel)
✓~ "Pine" SGA
FDA approved for treatment in those age 13 and older.
,Moderate metabolic risk.
Low EPS risk.
Risk for orthostatic hypotension, blood dyscrasias (neutropenia, leukopenia, and
agranulocytosis), QT prolongation, weight gain, and renal/hepatic impairment.
Asenapine (Saphris)
✓~ "Pine" SGA
FDA approved for age 10 and older.
Available as sublingual and patch.
Low metabolic risk.
Clozapine (Clozaril)
✓~ "Pine" SGA
Approved for treatment resistant schizophrenia and chronic suicidal behavior in
schizophrenia or schizoaffective disorder.
Not indicated for acute presentation of schizophrenia.
Low EPS risk.
, ANC must be >1500 when used and requires regular monitoring of WBC,
granulocyte, and neutrophil counts.
High metabolic risk, highest risk for weight gain, black box warning: may cause
severe neutropenia. Contraindicated in liver disease/failure. Not a first choice
treatment.
Clozapine monitoring schedule
✓~ Baseline ANC, CBC should be monitored weekly for 6 months, every 2 weeks
for months 6-12, then monthly thereafter. It is the only medication approved by FDA
for preventing suicide in clients with schizophrenia.
2 Dones and a Rone
✓~ SGA
Less sedating and cause less weight gain, but higher risk for hyperprolactinemia
and EPS.
Risperidone (Risperidol)
✓~ "Done" SGA
FDA approved for age 13 and older.
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