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NR507 Midterm Exam Questions And Answers Chamberlain $12.79   Add to cart

Exam (elaborations)

NR507 Midterm Exam Questions And Answers Chamberlain

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Serum ferritin levels are used to evaluate _______ status when diagnosing anemia. ~ Iron Clinical manifestations of left heart failure ~ - Orthopnea - Dyspnea - Coughing pink, frothy sputum - Crackles upon auscultation - Pulmonary edema Clinical manifestations of right heart failure ~...

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  • August 8, 2024
  • 22
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • NR507
  • NR507
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NR507 Midterm Exam
Questions And Answers
Chamberlain

Type 1 Hypersensitivity Reaction


✓~ - "Allergic reaction"

- Mediated by IgE.

- Inflammation d/t mast cell degranulation.

- Hay fever, hives (uticaria).

- Local s/s: itching, rash.

- Systemic: wheezing.

- Severe, systemic reaction: anaphylaxis: hypotension, severe bronchoconstriction.

- Main tx: epinephrine.




Type 2 Hypersensitivity Reaction


✓~ - Cytotoxic reaction; tissue specific

- Macrophages are the primary effectors cells involved


- Causes tissue damage or alters function

,- Examples: 1) Grave's disease- example of altering thyroid function, doesn't

destroy thyroid tissue. 2) ABO incompatibility- example of cell/tissue damage;

severe transfusion reaction occurs & the transfused erythrocytes are

destroyed by agglutination or complement-mediated lysis.




Difference between type 2 & 3 hypersensitivity reactions


✓~ - Type 2: organ specific; antibody binds to the antigen on the cell surface.

- Type 3: not organ specific; antibody binds to soluble antigen outside the cell

surface that was released into the blood or body fluids, and the complex is then

deposited in the tissues.




Type 3 Hypersensitivity Reaction


✓~ - Immune complex

- Antigen-antibody complex deposited in the tissues


- Neutrophils are the primary effector cell


- Causes autoimmune diseases


- Examples: rheumatoid arthritis (joints), systemic lupus erythematosus (SLE,

organs)

, Systemic Lupus Erythematosus (SLE)


✓~ - Facial rash confined to the cheeks (malar rash)

- Discoid rash (raised patches, scaling)


- Photosensitivity (skin rash d/t sunlight exposure)


- Oral or nasopharyngeal ulcers


- Hematologic disorders (hemolytic anemia, leukopenia, lymphopenia,

thrombocytopenia)


- Immunologic disorders


- Non-erosive arthritis of at least two peripheral joints


- Serositis (pleurisy, pericarditis)


- Renal disorder


- Neurologic disorders (seizures, psychosis)


- Presence of antinuclear antibody (ANA)




Autoimmunity

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