✓~ intact skin and mucous membranes (impermeable barrier)
PAMP
,✓~ pathogen associated molecular pattern
surfaces of bacteria, viruses, and other microbes are covered with many foreign
proteins
foreign
DAMP
✓~ damage associated molecular pattern
many proteins are released from inside our cells when they are damaged
foreign
PRR
✓~ pattern recognition receptors
surfaces of WBCs contain these receptor sites
,-continuously interact with any material they encounter to ID it as "self" or
"non-self" (foreign; PAMP or DAMP)
Chemotaxis
✓~ Cell movement that occurs in response to chemical stimulus
Phagocytosis
✓~ "cell eating"
1. opsonization and adherence
2. engulfment - WBC surrounds and ingests Ag
3. Fusion of phagosome with lysosome
4. destruction - phagosome digested by lysozyme, H202, acids, and other toxic
chemicals inside the lysosomes
5. egestion
Hypersensitivity Type 1:_____
✓~ Allergic reaction
, Hypersensitivity: Type 1
Mediated by ______
✓~ IgE
Hypersensitivity: Type 1
Inflammation due to _____________
✓~ mast cell degranulation
Hypersensitivity: Type 1
local symptoms
✓~ itching, rash
Hypersensitivity: Type 1
systemic symptoms
✓~ wheezing
Hypersensitivity: Type 1
most dangerous form
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller TestTrackers. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $13.49. You're not tied to anything after your purchase.