CITI Certification Exam Questions
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Which of the following is an example of how the principle of
beneficence can be applied to a study employing human
subjects? - ANS ✔Determining that the study has a maximization
of benefits and a minimization of risks.
Which of the following are the three principles discussed in
the Belmont Report? - ANS ✔Respect for Persons, Beneficence,
Justice
The Belmont Report's principle of respect for persons
incorporates at least two ethical convictions: first, that
individuals should be treated as autonomous agents, and
second, that: - ANS ✔Persons with diminished autonomy are
entitled to protection.
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CITI Cert
According to the authors, there are four common abuses that
historically are described as giving rise to vulnerability.
Which response below contains the correct four? - ANS
✔Physical control, coercion, undue influence, and manipulation
When an IRB is reviewing a research study and they are
considering if a potential subject population is vulnerable,
they should consider: - ANS ✔Is there a power differential
between researchers and subjects?
Subjects with a serious illness may be at risk for exploitation
because they may be desperate for a possible cure. This is an
example of: - ANS ✔Medical vulnerability
The NBAC looks at characteristics individuals might have that
would prevent them from being able to provide voluntary
informed consent. The traits may be thought of as falling into
six broad areas: cognitive or communicative, institutional,
deferential, medical, economic, and social. Prospective
research subjects who are not able to comprehend
information, deliberate, and make decisions about
participation in a proposed research study have a: - ANS
✔Cognitive or communicative vulnerability
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Which is an example of a situation where deferential
vulnerability might be a factor? - ANS ✔A physician recruiting
patients to be subjects
An example of an individual financial COI is: - ANS ✔A
researcher's spouse holds equity in a publicly traded
pharmaceutical company that is also the sponsor of the
researcher's study.
A researcher's membership on an advisory board with an
organization sponsoring research can create a COI because: -
ANS ✔It may be difficult for the researcher to appear neutral, as
the researcher may have an interest in the research's success
The COI management plan aims to: - ANS ✔Provide
procedures or extras steps to be taken to minimize the risk of bias
when a COI is disclosed
The peer review process can create conflicts of interest
because the choice of who reviews a potentially publishable
CITI Certification
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