Pharmacology N3300 - Mizzou Final Exam - Unit 5 Questions with Correct Answers
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RN- Nursing
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RN- Nursing
What are cholinergic receptors? What happens if you stimulate them or suppress them? correct answer A certain type of neuron whose molecular structure responds specifically to Acetylcholine
Two types 1. Muscarinic & Nicotinic
-Muscarinic: Stimulate: bradycardia, constriction of bronchi, increas...
Pharmacology N3300 - Mizzou Final Exam - Unit 5
Questions with Correct Answers
What are cholinergic receptors? What happens if you stimulate them or
suppress them? correct answer✔✔ A certain type of neuron whose
molecular structure responds specifically to Acetylcholine
Two types 1. Muscarinic & Nicotinic
-Muscarinic: Stimulate: bradycardia, constriction of bronchi, increase
sweating/salivation/gastric acid, contraction of bladder muscles,
relaxation of sphincter, increases GI movement
-Muscarinic: Suppress: tachycardia, decrease secretions, relax bronchi,
relax bladder, and relax GI
What main effects and side effects should you expect with
anticholinergic drugs? correct answer✔✔ Xerostomia, constipation,
CNS excitation, urinary retention, no sweat, ↓ secretions, blurred vision,
delusions, vasodilation
**ABCD'S = Anorexia, Blurry vision, Constipation/confusion, Dry
mouth, Sedation/stasis of urine
What do cholinesterase inhibitors do? What happens with an overdose?
correct answer✔✔ - Prevent the breakdown of Ach causing it to
accumulate in the synapses of all receptors (muscarinic, nicotinic)
benefits = NMJ
- OD = decrease force of contraction, excessive salivation, stop
breathing (MONITOR RR), groggy
, - tx = mechanical ventilation + atropine
How can you tell the difference between a myasthenic crisis and
cholinergic? correct answer✔✔ - If they are salivating a lot that means
the drug is toxic (CC: too much med) give atropine
- If you can't tell, give them edrophonium (ulta-fast CI inhibitor, if that
helps them then its a myasthenia crisis (not enough med) so tx w/
pyridostigmine)
When administering NMB to a patient what else should the nurse plan to
administer? What should they have at the bedside? correct answer✔✔
Bedside: O2, ambu-bag w/ mask, ventilation & intubation equipment.
Administer w/ sedation and/or pain meds because these drugs don't cross
BBB & don't impact cognitive function.
Why do you not give a patient levodopa with a nonselective MAO
inhibitor? correct answer✔✔ MAO inhibitors would block the dopamine
(which is what levodopa becomes when metabolized in the body)
How do cholinesterase inhibitors help alzheimer's disease? correct
answer✔✔ Increases the available ACh at the cholinergic synapse, and
enhances the non-damaged neurons transmission. SLOWS progression
does not stop it. ONLY for mild-moderate Alzheimer's.
What does atropine do? correct answer✔✔ - Anticholinergic use:
bradycardia & antidote for muscarinic agonist.
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