Exam (elaborations)
2024 NR565- ADVANCE PHARMACOLOGY EXAM WITH CORRECT ANSWERS
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2024 NR565- ADVANCE PHARMACOLOGY EXAM WITH CORRECT ANSWERS
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2024 NR565- ADVANCEPHARMACOLOGY EXAM WITH
CORRECT ANSWERS
What should be co-administered with febuxostat? - CORRECT ANSWERS-
NSAIDS or colchicine
NSAIDS
o Black Box Warning
o Drug interactions
o Therapeutic action
o Mechanism of action - CORRECT ANSWERS--NSAIDs may increase the risk
of myocardial infarction, stroke, and other thromboembolic events. NSAIDs
increase the risk for dangerous gastrointestinal adverse effects such as
bleeding, ulceration, and perforation.
-other NSAIDs, alcohol, warfarin (blood thinners), ACE inhibitors, and
diuretics
-relieve pain/discomfort, reduce inflammation, and bring down a high
temperature.
-inhibition of the enzyme cyclooxygenase (COX), decreased synthesis of
prostaglandins
Which schedule drugs can APRNs prescribe? - CORRECT ANSWERS-II-V
Who determines and regulates prescriptive authority? - CORRECT ANSWERS-
State Board of Nursing
How does limited prescriptive authority impact patients within the healthcare
system? - CORRECT ANSWERS-Longer wait times to sign a prescription
Limit practitioners that are needed in rural areas
Unequal relationships between providers.
Independent practitioners= more patients being seen= lessens the
patient/provider load
What are the key responsibilities of prescribing? - CORRECT ANSWERS-Safe
and competent practice
Understanding of the drugs, reactions, and pharmacology
Be aware of the age group you are prescribing to
, Most appropriate treatment approach for OA
Pharmacological and non-pharmacological - CORRECT ANSWERS-First line tx-
alendronate
Non Opioid medications - NSAIDs, cox-2 inhibitors
Nonpharmacologic tx - heat/cold, yoga, physical therapy, exercise, healthy
weight
Complications of untreated gout - CORRECT ANSWERS-Erosion and
irreversible joint damage, renal damage, tophi (stone deposits in joints and
tissues)
Treatment of acute flare of gout with colchicine
-Patient education
-Adverse effects - CORRECT ANSWERS--Only when needed to relieve an
attack:
-Start taking this medicine at the first sign of the attack for best results.
-Stop taking this medicine as soon as the pain is relieved or at the first sign
of nausea, vomiting, stomach pain, or diarrhea.
-Longer you wait to start with the attack, the less effective it might be
Long-term use of allopurinol
What condition can be developed? - CORRECT ANSWERS-SCAR (severe
cutaneous adverse reaction - rash, fever, eosinophilia, liver and kidney
function)
Drug interactions with allopurinol - CORRECT ANSWERS--Mercaptopurine and
azathioprine (immunosuppressants)
-Warfarin
-Theophylline
-Ampicillin
What should be used to make prescribing decisions? - CORRECT ANSWERS-
Documented provider-patient relationship
Not prescribing for family or friends
Documenting a thorough H&P, including discussions with the patient, and
drug monitoring/titrating.
Cost, guidelines, availability, interactions, side effects, allergies, hepatic and
renal function, need for monitoring, and special populations
Be familiar with pharmacokinetic and pharmacodynamic changes of older
adults and how that would translate to baseline information needed to
prescribe. - CORRECT ANSWERS-increase glomerular filtration rate leads to
increase drug excretion
increase hepatic metabolism
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