2024 ADVANCED
PHARMACOLOGY – MIDTERM
EXAM WITH CORRECT
ANSWERS
antiplatelet drugs - CORRECT ANSWERS-Decrease platelets ability to adhere
to one another. Used in patients at risk for: TIA, CVA, and MI example:
aspirin,clopidogrel
Fondaparinux (Arixtra) - CORRECT ANSWERS-Use: DVT prevention, PE with
warfarin, and acute DVT
Adverse effects: bleeding
Who oversees the APRN's prescribing of controlled substances?
a. The pharmaceutical board of the state
b. The federal government (DEA)
c. The practice protocols of the hospital
d. Practice agreements - CORRECT ANSWERS-b. The federal government
(DEA)
Warfarin (Coumadin) - CORRECT ANSWERS-Use: long-term prophylaxis of
thrombosis, A fib [antidote—Vit K]
Adverse effects: hemorrhage
INR 2-3 for most patients
Dabigatan Etexilate (pradaxa) - CORRECT ANSWERS-Use: prevention of stoke
and systemic embolism in patients with nonvalvular atrial fibrillation.
FDA found 150 mg bid has a better benefit/risk profile
Adverse effects: bleeding, GI
Nurse practitioner prescriptive authority is regulated by:
a. The National Council of Sate Board of Nursing
b. The State Board of Nursing for each state
c. The U. S. Drug Enforcement Administration
, d. The State Board of Pharmacy - CORRECT ANSWERS-b. The State Board of
Nursing for each state
Eight Information needed for the prescription - CORRECT ANSWERS-1. Date
of prescribing;
2. Name of patient(s);
3. Prescriber's name;
4. Name, strength, and dosage of drug or device;
5. Number of refills, if applicable;
6. Quantity prescribed in weight, volume, or number of units;
7. An indication of whether generic substitution has been authorized by the
prescriber;
8. Any change or alteration made to the prescription dispensed on contact
with the prescriber must show a clear audit trail.
Three additional required information for controlled substances - CORRECT
ANSWERS-1. Address of the prescriber and patient;
2. The prescriber's DEA number;
3 Controlled prescriptions shall also comply with all requirements of federal
and state controlled substance laws.
Bile Acid Sequestrants - CORRECT ANSWERS-Cholestyramine, Colestipol,
Colesevelam
Use: lower LDL, usually combined with statin
Adverse effects: constipation
Fibric Acid Derivatives (Fibrates) - CORRECT ANSWERS--Use: activates lipase,
suppresses fatty acid release from adipose, inhibits triglyceride synthesis in
liver, and increases secretion of cholesterol in bile
-Adverse: stomach upset, gall stones, prolonged prothrombin time (increased
clot time)
-Contraindications: severe kidney disease, gallbladder disease, cirrhosis
*combine with statin*
MEMORY TRICK: I need some FIBER STAT
Stable angina - CORRECT ANSWERS-predictable and consistent pain that
occurs on exertion and is relieved by rest and/or nitroglycerin.
ccbs use in angina - CORRECT ANSWERS-treat stable and variant angina
Ranolazine (Ranexa) - CORRECT ANSWERS-reduces the number of angina
episodes per week and increased exercise tolerance. can be combined with
nitrates, beta blockers, amlodipine
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