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NR 507- Advanced Patho Midterm Exam Questions With Correct Answers

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  • NR 507 ADVANCED PATHOPHYSIOLOGY

EXAM STUDY MATERIALS July 26, 2024 9:30 AM NR 507- Advanced Patho Midterm Exam Questions With Correct Answers Phsyiologic manifestation of anemia - answerSevere fatigue, pallor, weakness, dyspnea, dizziness Increased RBC distribution on labs Microcytic anemia - answerMCV <80fL Small RBCs ...

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  • August 5, 2024
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  • Exam (elaborations)
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  • NR 507 ADVANCED PATHOPHYSIOLOGY
  • NR 507 ADVANCED PATHOPHYSIOLOGY
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NR 507- Advanced Patho Midterm Exam
Questions With Correct Answers

Phsyiologic manifestation of anemia - answer✔✔Severe fatigue, pallor, weakness, dyspnea,
dizziness
Increased RBC distribution on labs

Microcytic anemia - answer✔✔MCV <80fL
Small RBCs
i.e. iron deficiency anemia, sideroblastic, thalassemia

Macrocytic anemia - answer✔✔MCV >100fl
Large RBCs
i.e. B12 deficiency, folate deficiency

Normocytic anemia - answer✔✔MCV 80-99fl
normal size RBCs
i.e. hereditary spherocytosis, acute blood loss, paroxysmal nocturnal hemoglobinuria

Hypochromic - answer✔✔decreased hemoglobin
low MCHC
RBCs pale color

Hyperchromic - answer✔✔increased hemoglobin
high MCHC
dark color

Normochromic - answer✔✔normal amount of hemoglobin
normal MCHC
Normal color

Causes of vitamin B12 deficiency - answer✔✔Decreased nutritional intake, impaired absorption




EXAM STUDY MATERIALS July 26, 2024 9:30 AM

, Risk factors for Vitamin B12 deficiency - answer✔✔vegetarian, GI issues (h. pylori), older
adults

S/S of Vitamin B12 deficiency - answer✔✔fatigue, peripheral neuropathy in BLE

Causes of folic acid deficiency - answer✔✔decreased dietary intake, increased requirement,
impaired utilization

Risk factors for folic acid deficency - answer✔✔alcoholism

Symptoms of folic acid deficiency - answer✔✔cheilosis, stomatitis, painful ulcerations of
mucosa, GI tract sensitivity

Iron deficiency anemia - answer✔✔Accompanied by low ferritin and transferrin levels
Low MCHC
Microcytic, hypochromic

causes of iron deficiency anemia - answer✔✔dietary deficiency, impaired absorption, increased
requirement, chronic blood loss

Thalassemia - answer✔✔Genetic with many possible mutations
Low MCHC

Anemia of chronic disease/inflammation - answer✔✔Initially normocytic-normochromic but
changes to microcytic-hypochromic
caused by decreased erythropoiesis and impaired iron utilization in those with chronic
disease/inflammation
i.e. CHF, CKD, infections

Hemolytic anemia - answer✔✔premature accelerated destruction of erythrocytes

Causes of hemolytic anemia - answer✔✔Acquired (transfusion reaction, hemolytic disease of
newborns, drug, infectious, etc.)
Genetic (structural defects, plasma protein mutation, enzyme deficiencies)

Aplastic anemia - answer✔✔normal MCHC
Suspect if levels of circulating erythrocytes, leukocytes, and platelets are also diminished

Sickle cell trait - answer✔✔Asymptomatic
Carry only one copy of hemoglobin gene

Sickle cell disease - answer✔✔Symptomatic



EXAM STUDY MATERIALS July 26, 2024 9:30 AM

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