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Pharmacology Androgens Exam 3 Questions And Answers
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Pharmacology Androgens Exam 3 Questions And Answers
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Pharmacology Androgens Exam 3Questions And Answers
Where is testosterone synthesized? (2)
- correct answer ✅95% - Leydig cells
5% - Adrenal
What are some other steroids secreted by the testes? (Select all that
apply)
A. Estrogen
B. Dihydrotestosterone (DHT)
C. Progesterone
D. Androstenedione
E. Dehydroepiandrosterone (DHEA)
F. Pregnenelone
- correct answer ✅B. Dihydrotestosterone (DHT)
C. Progesterone
D. Androstenedione
E. Dehydroepiandrosterone (DHEA)
F. Pregnenelone
What % of testosterone is bound in circulation and what is it bound to?
- correct answer ✅98% bound in circulation
65% - sex hormone-binding globulin (SHBG)
,Pharmacology Androgens Exam 3
Questions And Answers
33% - albumin
What % of circulating testosterone is free?
- correct answer ✅2%
What factors increase SHBG? (Select all that apply)
A. Thyroid hormone
B. Progesterone
C. Kidney disease
D. Estrogen
E. Liver cirrhosis
- correct answer ✅A. Thyroid hormone
D. Estrogen
E. Liver cirrhosis
What factors decrease SHBG? (Select all that apply)
A. Androgens
B. Growth hormone
C. Thyroid hormone
D. Liver cirrhosis
, Pharmacology Androgens Exam 3
Questions And Answers
E. Obesity
- correct answer ✅A. Androgens
B. Growth hormone
E. Obesity
In many peripheral tissues, testosterone is converted to
________________________ (DHT/DHEA) by ______________ (5-a
reductase/17-beta hydroxylase)
- correct answer ✅DHT/5-a reductase
Testosterone can be converted to ____________(Estradiol/Estrogen) by
___________ (5-a reductase/p450 aromatase) in fat, liver and
______________ (pituitary/hypothalamus).
- correct answer ✅Estradiol/P450 aromatase/hypothalamus
What are the adrenal products associated with androgens? (Select all
that apply)
A. Androstenedione
B. Estrogen
C. Progesterone
D. Dehydroepiandrosterone (DHEA)
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