What is the most common gastrointestinal syndrome in the U.S.? - ✔✔-Irritable bowel syndrome (IBS)
What is IBS characterized by? - ✔✔-characterized by recurrent abdominal pain and altered bowel habits
without a clear organic cause
Based on studies, individuals with IBS likely have one or more abnormalities in the following areas: -
✔✔-Visceral hypersensitivity
-Alterations in intestinal microflora
-Food sensitivity
-Psychological features
VISCERAL HYPERSENSITIVITY
Compared to normal patients, patients with IBS exhibit what following a meal? - ✔✔-Patients with IBS
exhibit greater colonic motor activity following meals compared to normal subjects
-Similar results have been found with inflation of a rectal balloon
VISCERAL HYPERSENSITIVITY
In patients with IBS, what seems to stimulate exaggerated colonic motility? - ✔✔-eating and rectal
distention
VISCERAL HYPERSENSITIVITY
What is the peak amplitude of high-amplitude propagating contractions (HAPCs) in patients with IBS? -
✔✔-IBS patients also seem to have greater peak amplitude of highamplitude propagating contractions
(HAPCs)
, VISCERAL HYPERSENSITIVITY
In IBS, a correlation exists between what and the reproduction of pain? - ✔✔-A correlation exists with
the entry of food contents into the cecum and the reproduction of pain
-Studies performed reproducing colonic distention result in greater pain in patients with IBS compared
to normal individuals
VISCERAL HYPERSENSITIVITY
For many patients with IBS, what practice will result in an
improvement in symptoms? - ✔✔-Fasting
ALTERATIONS IN INTESTINAL MICROFLORA - ✔✔-Although an infectious etiology has never been
identified, several studies have demonstrated signs that patients with IBS may have alterations in their
colonic microflora.
-Some patients with IBS have findings suggestive of small intestinal bacterial overgrowth.
-Counter to this line of reasoning is the fact that erroneous test results can occur secondary to rapid
small bowel transit.
ALTERATIONS IN INTESTINAL MICROFLORA
Many patients with IBS will report that their symptoms began after an episode of what? - ✔✔-
gastroenteritis
ALTERATIONS IN INTESTINAL MICROFLORA
What causes of gastroenteritis resulted in the development of IBS? - ✔✔-Campylobacter
-Salmonella
-Shigella
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