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AGA Clinical Practice Guideline on the Pharmacological Management of Irritable Bowel Syndrome with Diarrhea Exam | Questions & Answers (100 %Score) Latest Updated 2024/2025 Comprehensive Questions A+ Graded Answers | With Expert Solutions$13.48
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AGA Clinical Practice Guideline on the Pharmacological Management of Irritable Bowel Syndrome with Diarrhea Exam | Questions & Answers (100 %Score) Latest Updated 2024/2025 Comprehensive Questions A+ Graded Answers | With Expert Solutions
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Course
Irritable Bowel Syndrome
Institution
Irritable Bowel Syndrome
AGA Clinical Practice Guideline on the Pharmacological Management of Irritable Bowel
Syndrome with Diarrhea Exam | Questions & Answers (100 %Score) Latest Updated
2024/2025 Comprehensive Questions A+ Graded Answers | With Expert Solutions
AGA Clinical Practice Guideline on the Pharmacological Management of Irritable Bowel
Syndrome with Diarrhea Exam | Questions & Answers (100 %Score) Latest Updated
2024/2025 Comprehensive Questions A+ Graded Answers | With Expert Solutions
Irritable Bowel Syndrome - ✔✔Common disorder of gut-brain interaction with 4.1%-10.1% worldwide
prevalence among adults.
Quality of Life - ✔✔Patients with IBS have worse health-related QOL than patients with diabetes or end-
stage renal disease.
IBS-D - ✔✔Irritable bowel syndrome with predominant diarrhea, affecting 30%-40% of IBS cases.
Eluxadoline - ✔✔Minimally absorbed mixed m- and k-opioid receptor agonist and d-opioid receptor
antagonist for IBS-D.
Rifaximin - ✔✔Nonabsorbable, oral antibiotic for IBS-D, FDA-approved at 550 mg 3 times per day for 14
days.
Sphincter of Oddi spasm - ✔✔A condition associated with rifaximin, contraindicated in patients with a
history of alcohol abuse.
Selective Serotonin Reuptake Inhibitors - ✔✔Conditionally not suggested for use in patients with IBS.
Antispasmodics - ✔✔Conditionally suggested for use in patients with IBS.
Grading of Recommendations Assessment, Development, and Evaluation (GRADE) - ✔✔Framework used
to assess evidence and make recommendations.
Evidence-to-Decision Framework - ✔✔Used to develop recommendations based on evidence, patient
values, and preferences.
, PICO format - ✔✔Format used to outline patient population, intervention, comparator, and outcome(s)
for each clinical question.
FDA Responder End Point for IBS-D - ✔✔Defined as a participant reporting a 30% reduction in average
daily worst abdominal pain scores and a 50% reduction in number of days per week with at least 1 stool
that has a consistency of type 6 or 7.
European Medicines Agency Responder End Point - ✔✔Similar to the FDA responder end point, but for
13 of 26 weeks.
Bristol Stool Form Scale (BSFS) - ✔✔Scale used to measure stool consistency, with type 6 or 7 indicating
diarrhea.
Rome IV Criteria - ✔✔Symptom-based diagnostic criteria for IBS.
Contraindicated - ✔✔Not recommended due to potential harm or adverse effects.
Moderate Certainty - ✔✔Level of confidence in the effect estimate, likely close to the true effect but
with a possibility of substantial difference.
Very Low Certainty - ✔✔Very little confidence in the effect estimate, likely to be substantially different
from the estimate of effect.
Primary Care - ✔✔Health care professionals providing basic medical services for common illnesses and
preventive care.
Gastroenterology Health Care Professionals - ✔✔Specialized health care professionals focusing on the
digestive system.
Policy Makers - ✔✔Individuals involved in the development and implementation of health care policies.
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