My document describes biochemistry the chapter hormones really good. It’s a summary for all important Hormones. To understand the hormones just have to read this summaries and you will be more than fine.
Test Bank - Lehninger Principles of Biochemistry, 8th Edition (Nelson, 2022), Chapter 1-28 | All Chapters
TEST BANK FOR LEHNINGER PRINCIPLES OF BIOCHEMISTRY NELSON 6TH EDITION
TEST BANK FOR LEHNINGER PRINCIPLES OF BIOCHEMISTRY 6TH EDITION BY NELSON
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HORMONES IN PHOSPHO-CALCIUM METABOLISM:
(regulation of Calcemia)
1. PTH Parathormone (produced by parathyroid gland)
Produced in the form of a precursor, has to be ACTIVATED:
1. Pre Fragment of amino acid is removed in the ER.
2. Pro Fragment of amino acid is removed in the golgi,
Activating PTH.
Biological effects:
2. Calcitonin ROLE
- Controlled by calcium levels. ✓
1. 7 dehydrocholesterol & Ergosterol Converted into vitamins
cholecalciferol (D3) and Ergocalciferol (D2) in the skin via
UV radiation (photolysis).
2. D3 & D2 are activated by 2 hydroxylations
(position 25 in liver and position 1 alpha in kidneys,
activated by PTH, which is activated from hypocalcemia)
Into 1 alpha, 25 (OH)2 calciferol.
REGULATIONS:
During Hypercalcemia calciferol
becomes inactive due to extra
hydroxylation (position 24).
3. Calcitriol
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