CEN TOXICOLOGY QUESTIONS And Answers Graded A+!!!!
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Course
CEN.
Institution
CEN.
Anticholinergics [not producing fluids/blood to heart, lungs and brain] syndrome
(antihistamines, bronchodilators, cyclic antidepressants, SLEEP AIDS) - ANS Hot as a hare (hyperthermia)
Red as a beet (flushed)
Dry as a bone [ANHYDROSIS (dry skin, urinary retention)
Blind as a bat (myd...
CEN TOXICOLOGY QUESTIONS And
Answers Graded A+!!!!
Anticholinergics [not producing fluids/blood to heart, lungs and brain] syndrome
(antihistamines, bronchodilators, cyclic antidepressants, SLEEP AIDS) - ANS Hot as a
hare (hyperthermia)
Red as a beet (flushed)
Dry as a bone [ANHYDROSIS (dry skin, urinary retention)
Blind as a bat (mydriasis)
Mad as a hatter (hallucinations, delirium, myoclonic jerking)
The antidote for anticholinergic toxicity is physostigmine salicylate. Physostigmine is the only
reversible acetylcholinesterase inhibitor capable of directly antagonizing the CNS manifestations
of anticholinergic toxicity; it is an uncharged tertiary amine that efficiently crosses the
blood-brain barrier
What does muscular rigidity cause - ANS rhabdomylosis syndrome due to a direct or
indirect muscle injury. It results from the death of muscle fibers and release of their contents into
the bloodstream (myoglobin). This can lead to renal (kidney) failure.
sympathomimetic [fight or flight/shunt blood going to heart/brain/lungs] - ANS MIMIC
SYMPATHETIC
a drug that stimulates the sympathetic branch of the autonomic nervous system
Epinephrine, adrenaline
Organophosphate poisoning
Cholinergics {see, spit, pee, shit] used in pesticides b/c - ANS BUGS DROWN with
Cholinergic [producing fluids: saliva, urine, digestive enzymes]
Organophosphates are used as insecticides, medications, and nerve agents. Symptoms
include increased saliva and tear production, diarrhea, vomiting, small pupils, sweating, muscle
tremors, and confusion.
Cholinergics {see, spit, pee, shit] pathway - ANS muscuric and nicotinic receptors that use
acetylcholine neurotransmitters
cholinergic cells that use which neurotransmitter - ANS Referring to cells that use
acetylcholine as their synaptic transmitter.
Cholinergic Drug toxicity
antidote - ANS 2-PAM
Atropine
anticholinergic over dose examples - ANS Atropine
antihistamines [benadryl]
TCAs Tricyclic antidepressants (Amitriptyline)
Cyclobenzapine (muscle relaxant)
extrapyramidal effects are? - ANS Extrapyramidal symptoms are most commonly caused
by typical antipsychotic drugs that antagonize dopamine D2 receptors. The most common
typical antipsychotics associated with EPS are haloperidol and fluphenazine.
drug-induced movement disorders that include acute and tardive symptoms
Saran Gas [nerve gas] - ANS Within seconds of exposure to sarin gas (or liquid, which
evaporates easily), we start to notice the immediate effects of acetylcholine buildup. First, our
smooth muscles and secretions go crazy. The nerves to those areas keep firing, keep telling
them to go
Saran Gas nerve gas antidote - ANS 2-PAM Cl
Atropine and pralidoxime chloride (2-PAM Cl) are antidotes for nerve agent toxicity; however,
2-PAM Cl must be administered within minutes to a few hours (depending on the agent)
following exposure to be effective. There is also generally no benefit in giving more than three
injections of 2-PAM Cl.
nerve gas tx - ANS FIRST RESPONDERS AT THE SCENE
atropine until they stop pouring fluid out of their face
Pulmonary Edema Needs Positive Pressure Airway
OD/Chronic use of benzodiapines (clonazepam
diazepam, lorazepam) - ANS Intractable Szes
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