WGU D027 Study Guide
1. Autosomal Dominant 1 parent has, 50% change of child having
2. Autosomal Recessive Both parents are carriers, 25% change of
child having, 50% chance child is a carrier.
3. Cystic Fibrosis affects pancreas causing secretions in
lungs
4. 21st Trisomy Down Syndrome
5. Kl...
1. Autosomal Dominant 1 parent has, 50% change of child having
2. Autosomal Recessive Both parents are carriers, 25% change of
child having, 50% chance child is a carrier.
3. Cystic Fibrosis affects pancreas causing secretions in
lungs
4. 21st Trisomy Down Syndrome
5. Klinefelter Syndrome (XXY) male has extra X, female like qualities
6. Turner Syndrome Missing X in females
7. Alpha Thalassemia inherited blood disorder; mild to severe
anemia
8. Beta Thallasemia low hemoglobin; contraindicated medica-
tion ferrous sulfate
9. Prevalence Risk proportion of the population affected at a
certain time
10. Incidence rate number of new cases divided by popula-
tion
11. Innate immunity inflammation; increased vascular perme-
ability
12. B&T lymphocytes immune response
13. primary malignant tumor lack of organization of cells
14. glucocorticoids used in combination with other agent
to treat lymphoid tissue (leukemia). glu-
cocorticoids are directly toxic to lymphoid
tissues.
15. Selective estrogen receptor
modulators (SERM)
, WGU D027 Study Guide
for hormone receptor positive and ad-
vanced breast cancer. (Tamoxifin reduces
risk and recurrence risk)
16. Heart failure impairment of the ventricle to fill with or
eject blood; heart cannot meet metabolic
need of the body.
17. CHF heart cannot keep up with metabolic
needs; volume overload in pulmonary
area
18. Left Ventricular Dysfunction reduced ejection fraction; ventricle having
issue ejecting blood.
19. normal ejection fraction 55 - 60 % (blood pumped out with each
heartbeat)
20. Ejection fraction of 50% - re- preserved
duced or preserved?
21. Diastolic CHF preserved ejection fraction, problem is
with filling
22. Systolic CHF reduced ejection fraction, problem is with
ejecting
23. Left sided CHF pulmonary (JVD, fluid volume overload,
rails, S-3 murmurs) ** #1 cause of Right
sided CHF
24. BNP gold standard lab test to diagnose CHF
25. Echocardiogram Diagnostic tool, evaluates heart structure
and function
26. At Risk for HF - Stage A no structural heart disease or symptoms
of heart failure
27. Stage A HF co-morbidities
, WGU D027 Study Guide
htn, atherosclerotic disease, diabetes,
metabolic syndrome, patients using car-
diotoxins with family history
28. Therapy goals of stage A HF treat htn, encourage smoking cessation,
encourage regular exercise, treat lipid
disorders, discourage alcohol intake/drug
use, control metabolic syndrome
Meds: ACEI or Angiotensin II RB for vas-
cular disease or diabetes (avapro, losar-
tan, benicar, diovan, etc)
29. At Risk for HF - Stage B structural heart disease but no symptoms
of heart failure
30. Stage B HF co-morbidities previous MI, LV remodeling with LV hyper-
trophy and low EF, asymptomatic valvular
disease
31. Therapy goals of Stage B HF Meds: ACEI or ARB, Beta-blockers, in-
plantable defibrillators
32. Stage C heart failure structural heart disease with prior or cur-
rent symptoms of HF
33. Presentation of Stage C HF known structural heart disease and short-
ness of breath and fatigue, reduced exer-
cise tolerance
34. Therapy for Stage C HF dietary salt restriction, MEDS: diuretic,
ACEI, beta blockers. Some patients: al-
dosterone antagonist, ARBs, digitalis, hy-
dralazine/nitrates, biventricular pacing, in-
plantable defibrillators
35. Stage D heart failure refractory HF requiring specialized inter-
ventions
36. Presentation of Stage D HF marked symptoms at rest despite maxi-
mal medical therapy (recurrently hospital-
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