NUR 254 CHAP 38
Exam Questions
with Complete
Solutions Graded
A+
Denning [Date] [Course title]
, Allergy - Correct Ans: An inappropriate, often harmful response of the immune system to normally
harmless substances
Hypersensitive reaction to an allergen initiated by immunologic mechanisms that is usually mediated by
IgE antibodies
Allergen - Correct Ans: the substance that causes the allergic response
Atopy - Correct Ans: refers to the allergic reactions characterized by IgE antibody action and a genetic
predisposition
Immunoglobulins and Allergic Response - Correct Ans: Antibodies (IgE, IgD, IgG, IgM, and IgA) react with
specific effector cells and molecules and function to protect the body
IgE antibodies are involved in allergic disorders.
IgE molecules bind to an allergen and trigger mast cells or basophils.
These cells then release chemical mediators such as histamine, serotonin, kinins, SRS-A, and neutrophil
factor.
These chemical substances cause the reactions seen in allergic response.
Allergic Reaction - Correct Ans: Allergen triggers the B cell to make IgE antibody, which attaches to the
mast cell. When that allergen reappears, it binds to the IgE and triggers the mast cell to release its
chemicals.
Chemical Mediators - Correct Ans: Primary
Histamine
Eosinophil chemotactic factor of anaphylaxis
Platelet-activating factor
Prostaglandins
Secondary
Leukotrienes
Bradykinin
Serotonin
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