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Midterm Exam NR565 NR 565 Advanced Pharmacology Care of the Fundamentals Exam Questions and Verified Answers (2024/ 2025 Update) Chamberlain$7.99
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MIDTERM EXAM NR565 NR 565 ADVANCED PHARMACOLOGY
CARE OF THE FUNDAMENTALS EXAM QUESTIONS AND
VERIFIED ANSWERS (2023 2024 UPDATE) CHAMBERLAIN
1. ASCVD Risk Score: Used in children aged 9-11 and 19-21, and adults every 5 years
after 20, with greater risk for those with diabetes and a risk score >7.5%
2. Ezetimibe Use: Can be used in pregnancy/breastfeeding, as monotherapy or adjunct
therapy with a statin or fibrate
3. Ezetimibe: Cholesterol Absorption Inhibitor that lowers cholesterol levels by
decreasing absorption from the small intestine, without affecting triglycerides
4. Lifestyle Changes for High Cholesterol: Non-drug measures to lower LDL,
including diet, exercise, weight control, and smoking cessation
5. Minimizing Side Effects: Non-statins like fibrates, ezetimibe, bile acid sequestrants,
or statins for generally well-tolerated side effects
6. Organic Nitrates Therapeutic Action: Direct relaxant effect on vascular smooth
muscles, dilation of coronary vessels, reduction of preload and afterload, and
promotion of vasodilation
7. Ranolazine Contraindications: Inhibited by CYP3A4 inhibitors, increasing the risk
of torsades de pointes, including grapefruit juice, HIV protease inhibitors, macrolide
antibiotics, azole antifungal drugs, and some CCB
8. Statin Prescription Age: Avoid in children under 10
9. CCB Role in Variant Angina: Promotes relaxation of coronary artery spasm,
increasing cardiac oxygen supply
10. HF Worsening Symptoms Medication: Aldosterone antagonist that promotes
myocardial remodeling and fibrosis to help with symptoms
11. CCB Stable Angina: Promotes relaxation of peripheral arterioles, decreasing
afterload and reducing cardiac oxygen demand
12. Nitro Patches Side Effect Response: Prescribe a BB to help with increased heart
rate
13. CYP450 Inhibitors and Reducers: When not used correctly, they lead to
increased side effects, adverse reactions, and toxicity
14. Gouty Arthritis Treatment Decision: In patients with infrequent flareups (less
than three per year), NSAIDs are the first line agent for relieving pain
15. Gouty Arthritis NSAID Ineffectiveness: Prescribe a glucocorticoid (prednisone)
or make dietary changes
16. Colchicine Long Term Treatment: Considered for long term treatment if a
person has three or more gouty attacks per year
1/5
, .
17. Colchicine Contraindications: Should not be taken with statins or CYP3A4
inhibitors
18. Colchicine Adverse Effects: Nausea, vomiting, diarrhea, myelosuppression,
myopathy, and rhabdomyolysis
19 Allopurinol Long Term Effect: Can lead to severe cutaneous adverse reaction
(SCAR) with symptoms like rash, fever, eosinophilia, and liver and kidney function
issues
20. Febuxostat Co-Administration: Should be co-administered with NSAIDs or
colchicine
21. Untreated Gout Complications: Erosion and irreversible joint damage, renal
damage, and tophi formation
22. Alendronate Patient Education: Minimize risk of esophagitis by swallowing the
pill whole with a full glass of water, then sitting up for at least 30 min, and taking the
med 30 min prior to other intake
23. Ibandronate Dietary Supplement Interference: Interferes with calcium,
magnesium, and iron absorption
24. Osteoporosis 1st Line Treatment: Alendronate is the first line treatment
25. Allopurinol Safety in Renal Dysfunction: Safe to use in patients with renal
dysfunction or who over produce uric acid
26. DMARDs Baseline Diagnostics: Includes CBC with WBC differential, s/s of
infection, malignancies, pregnancy rule out, ALT, AST, serum creatinine, comprehensive
history and physical exam, and assessment of immunocompetence and liver and renal
status
27. Methotrexate Baseline Data: Includes chest x-ray with emphasis on pulmonary
and GI status
28. DMARD Requiring Ophthalmologic and Cardiac Exam: Hydroxychloroquine
29. Raloxifene Black Box Warning: Risk for venous thromboembolic events (DVT,
PE, stroke)
30. Controlled Substance Addiction Predictors: Reinforcing properties of drugs,
physical and physiological dependence, social factors, drug availability, individual
vulnerability, impulsivity, low tolerance for frustration, and specific personality
disorders
31. Pregabalin Chronic Pain Treatment: Adjuvant analgesic for neuropathic pain,
effective in diabetic neuropathy, seizures, central neuropathy, postherpetic neuralgia,
and fibromyalgia
32. Pregabalin Adverse Effects: Sedation, drowsiness, dizziness, ataxia, blurred vision,
and difficulty thinking
33. GI Bleeding Link: Linked to COX-2 inhibitors and NSAIDs
2/5
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