Pharmacology 1 Exam #3 (Ameritech) -Questions with Correct Answers/ Latest Update/ 100% Pass Prototype drug of benzodiazepines - ✔✔Alprazolam (Xanax) Other benzodiazepines to know - ✔✔-Diazepam (Valium -Lorazepam (Ativan) -Clonazepam (Klonopin) Benzodiazepines suffixes - ✔✔"lams, pams" Benzodiazepines therapeutic uses - ✔✔Anti-anxiety Benzodiazepines adverse effects - ✔✔-CNS depression (sedation, lightheadedness, ataxia, decreased cognitive function) -Anterograde amnesia -Toxicity (oral and IV diazepam, lorazepam - administer flumazenil) -Paradoxical response (insomnia, excitation, euphoria, anxiety, rage) -Withdrawal effects Benzodiazepines contraindications - ✔✔-Sleep apn ea -Pregnancy -Breastfeeding -Respiratory depression -Glaucoma -Liver disease -Mental illness -Substance use disorder Benzodiazepines interactions - ✔✔-Alcohol -Barbiturates -Opioids -Grapefruit juice (reduces absorption) -High fat meals (reduces absorption) Benzodiazepines medication administration - ✔✔-Administer Flumazenil for benzodiazepine overdose/toxicity -Schedule IV drug Benzodiazepines nursing interventions - ✔✔-Monitor vitals -Neuro assessment (pupil reaction, strength) -Respiratory assessment Benzodiazepines client education - ✔✔-No alcohol -Take in a safe place -Taper medications -Do not operate heavy machinery -Pregnancy risk (D) -Take at bedtime -Use short term due to risk of dependence -Schedule IV drug -No grapefruit juice (reduces metabolism) -No high fat meals (reduces metabolism) Prototype drug of atypical/nonbarbiturate anxiolytic - ✔✔Buspirone (Buspar) Buspirone (Buspar) therapeutic uses - ✔✔Anti-anxiety (short -term) Buspirone (Buspar) adverse ef fects - ✔✔-Suicidal ideation -Risk for serotonin syndrome (with concurrent use of SSRIs) -Hypertensive crisis (with concurrent use of MAOIs) Buspirone (Buspar) contraindications - ✔✔-Suicide risk -Depression -Older adults -Liver dysfunction -Renal dysfunction Buspirone (Buspar) interactions - ✔✔-SSRIs -MAOIs -Ketoconazole -Erythromycin -St. John's Wart -Grapefruit Juice Buspirone (Buspar) medication administration - ✔✔Not suitable for for PRN dosing Buspirone (Buspar) client education - ✔✔-Do not take medication as needed -Medication can take 2 -6 weeks to produce a therapeutic effect -Medication is nonaddictive -Meant for short term use but can be used for up to 1 year -Don't drink grape juice with this medication -No CNS depressant effects Prototype drug of Selective Serotonin Re -uptake Inhibitors (SSRIs) for depression - ✔✔Fluoxetine (Prozac)
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