Advanced Pharmacology Exam 1
1.Prescription writing: required pt and prescriber info: Patient's name and
full address
Date of prescription
Prescriber's full name, address, and phone number Prescriber's DEA # if controlled substance
2.Prescription writing: required drug info: Name (don't abbreviate) Strength and vehicle
Dosage
Route of administration
Directions (Sig) for taking the med: frequency, timing, details specific to drug Amount to be dispensed
Refills
3.Critical Rx Information?: DAW vs generic, refill #, dose form, length of thera- py/quantity, pt Ax, date of Rx, route, signature, DEA #
4."Rational" Prescribing Process, WHO: Choose a rational treatment Selection of P-drugs (Personal drugs)
Treating the pt (select, Rx, monitor) Keeping up-to-date
5.What are P-drugs?: P(ersonal) drugs - those that you are going to prescribe regularly and with which you become familiar
6.Steps of Rational Prescribing: Define the pt's problem Specify the therapeutic objective
Choose Tx
Verify: efficacy, safety, suitability, cost Start Tx (write a clear Rx)
Educate! Give inform instructions, warnings Monitor treatment
7.What is DAW in prescribing?: Dispense as written
8."Rights" of a prescription: Patient Medication
Dose
Rout
e Dose schedule
Does this make sense for this drug, patient, situation?
9.Pharmacokinetics: How the body affects a drug
10.Pharmacodynamics: How a drug affects the body - effects that occur at the cellular and systemic levels
11.Pharmacogenomics: General study of how one's individual genetic variation affects drug behavior .Four components of pharmacokinetics: ADME - absorption, distribution, me- tabolism, excretion
13.Absorption: How (well) does the body uptake the drug?
14.Distribution: Transportation of the drug to the site of
action How (well) is the drug carried to the site of action?
15.Elimination: How (well) is the drug cleared from the body?
16.All types of absorption are affected by...: Drug properties (molecular weight, lipid solubility) pKa, drug formulation, disintegration time, dissolution rate)
17.Enteral Absorption - GI tract - affected by? (4 things): Blood flow to area of absorption
First pass effect
Cellular membrane permeability (passive vs. active)
GI motility (absence/presence of food in stomach, other drugs)
18.Parenteral Absorption - affected by? (2 things): Blood flow to area of absorp- tion
Cell membrane permeability (passive vs. active transport)
19.Bioavailability: Percentage of a drug that reaches the systemic
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