Toxic to just about every organ except to heart, toxicity made worse with aspirin
SE:
-N/V
-hyperuricemia
Melphalan (Alkeran) - ANS-alkylating agent
-breast, ovarian, neuroblastoma
SE: N/V
Oxaliplatin (Eloxatin) - ANS-alkylating agent
-colorectal, pancreatic
SE:
-N/V/D
- sensitivity to cold
-hepatic and neurotoxic
-allergic reaction
-laryngopharyngeal dysesthesia (A disorder characterized by an uncomfortable persistent sensation in
the area of the laryngopharynx)
Temozolomide (Temodar) - ANS-alkylating agent
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