NUR 334 Pharmacology I EXAM 4 Modules 7 and 8 Exam (Reproductive, GI, Musculoskeletal) LATEST 2024 GUARANTEED PASS Medroxyprogesterone (Depo -Provera, Depo -SubQ Provera) Medications to treat dysfunctional uterine bleeding Oxytocin (Pitocin) Uterine stimulant Terbutaline (Beta 2 Adrenergic agonist) Uterine relaxant mifepristone (Mifeprex) Abortifacients (pharmacologic abortion) levonorgestrel (Plan B) Emergency contraception testosterone Prototype for androgens Sildenafil (Viagra: PDE -5 inhibitor) Prototype for erectile dysfunction finasteride (Proscar: 5 -alpha reductase inhibitor); tamsulosin (Flomax: alpha 1 adrenergic receptor antagonist) Prototypes for benign prostatic hyperplasia Estradiol, Norethindrone estrogen contraceptives Monophasic contraceptives provide a fixed concentration of hormones throughout the entire cycle with a "pill -free period" for a week during use of the pill Biphasic contraceptives Fixed estrogen dosed combined with a low progesterin dose for the first 10 days and a higher dose for the rest of the cycle. Available in 21 or 28 day packages Triphasic contraceptives contains three different doses of hormones in the pill that changes each week throughout the cycle preventing pregnancy; when an appropriate combination of estrogen and progestin is in the bloodstream, release of FSH and LH is inhibited, thus preventing ovulation Mechanism of action of estradiol and norethindrone hypertension, thromboembolic disorders Adverse effects of estradiol and norethindrone cigarette smoking, coronary artery disease, stroke, thromboembolic disorders, breast cancer or any estrogen -fed cancer, history of jaundice with oral contraceptive use or pregnancy, liver tumors, known or suspected pregnancy Contraindications of estradiol and norethindrone tranexamic acid (increased risk for thromboembolic events); rifampin, some antibiotics, barbiturates, anticonvulsants, protease inhibitors, antifungals (decrease effectiveness of contrac eptives); warfarin, heparin, certain other anticoagulants have decreased effectiveness due to contraceptives Drug interactions with estradiol and norethindrone mood disturbances, depression, irritability, insomnia, hot flashes, irregular menstrual cycles , headaches Symptoms of early menopause vaginal atrophy, increased infections, painful intercourse, skin atrophy, stress urinary incontinence, sexual disinterest
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