100% satisfaction guarantee Immediately available after payment Both online and in PDF No strings attached
logo-home
APEA PRE-PREDICTOR EXAM LATEST ACTUAL EXAM 400+ QUESTIONS AND ANSWERS EXAM NEWEST 2024 ACTUAL EXAM 400+ QUESTIONS AND CORRECT DETAILED ANSWERS VERIFIED ANSWERS ALREADY GRADED A+ $19.49   Add to cart

Exam (elaborations)

APEA PRE-PREDICTOR EXAM LATEST ACTUAL EXAM 400+ QUESTIONS AND ANSWERS EXAM NEWEST 2024 ACTUAL EXAM 400+ QUESTIONS AND CORRECT DETAILED ANSWERS VERIFIED ANSWERS ALREADY GRADED A+

 10 views  0 purchase
  • Course
  • APEA PRE-PRED
  • Institution
  • APEA PRE-PRED

A 15 years old high school student with a mild sore throat and low-grade fever that has persisted for about 3 weeks. She reports general malaise, fatigue, and loss of appetite. The NP suspects mononucleosis. Which of the following is the LEAST appropriate intervention? Palpate the lymph n...

[Show more]

Preview 3 out of 29  pages

  • June 6, 2024
  • 29
  • 2023/2024
  • Exam (elaborations)
  • Questions & answers
  • APEA PRE-PRED
  • APEA PRE-PRED
avatar-seller
NurseEdwin
NMTCB PET certification Review 2023 -2024 questions with correct answers GRADED A Rb-82 Gener taor Alert Level - ✔✔ 14L of eleute volume reached, or Sr -82 level 0.002uCi/mCi of Rb -82, or Sr -85 level 0.02uCi/mCi of Rb -82 Actions for Rb82 Generator Alert Level - ✔✔ Test after every 750 mL has passed through generator Stop using Rb -82 generator if - ✔✔17L of eleute volume reached, or 42 days post calibration date, or Sr82 levenis 0.01uCi/mCi of Rb82, or Sr85 level reaches 0.1uCi/mCi of Rb82 Cyclotron produced isotopes and half -life - ✔✔ C11, 20.3 min; N13 9.97 min; O15 2.03 min; F18, 109.7 min Advanta ges of negative ion cyclotrons - ✔✔ 1) less nuclear activation of cyl potion cavity and surroundings, 2) can self -focus beam of particles, 3) can irradiate 2 targets at once Isotopes produces by negative ion cyclotrons - ✔✔ C, N, O = metabolites Reaction f or chemical labeling of F18 -FDG - ✔✔ Nucleophilic substitution Chemical reaction of FDG - ✔✔ Electron rich group of atoms change place on molecule with a positively charged leaving group Precursor molecule for FDG - ✔✔ Mannose triflate Chem formula of FDG - ✔✔ 2-deoxy -2-[18F]fluoro -D-glucose. (Fludeoxyglucose F -18) Intermediate step in FDG synthesis - ✔✔ Alkaline hydrolysis of 4 acetyl groups by replacing with OH Size filter used after purification - ✔✔ 0.22 um FDA ref for PET pharma pro duction - ✔✔ General chapter 823 FDG QA appearance - ✔✔ Colorless liquid FDG QA radiochemical identity - ✔✔ Thin -layer chromatography Rf value to reference standard FDG QARadionuclide identity - ✔✔ Half-life 105 and 115 minutes FDG QA bacterial endotoxins test - ✔✔ LAL (Limulus amebocyte lysate) <175 USP endotoxins units per max volume injection; endotoxins< 17.5 EU FDG QC pH - ✔✔ Between 4.5 to 7.5 FDG QA Radiochemical purity - ✔✔ Thin -layered chromatography radioactive Rf should be not less than 90% of tot al radioactivity of chromatography plate FDG QC Radionuclideic purity - ✔✔ should be >99.5% of radionuclidie specified. tested using multi -
channel analyzer with peaks at 0.511 and 1.022 MeV FDG QC chemical purity - ✔✔ testing depends upon synthesis method used to create FDG Kryptofix 222 - ✔✔ FDG QC chemical purity test - thin-layer paper chromatography spot test. 50 ug/mL and FDG solution must demonstrate a less intense response than standard 2-Chloro -2-deoxy -D-glucose - ✔✔ FDG QC chemical purity test used if hydrolysis step was performed with hydrochloric acid. Use high -performance liquid chromatography using an electrochemical detector. Mus not have more than 1 mg CLDG: 2 -deoxy -2-D-glucose FDG QC Residual solvents - ✔✔ solvents can be in FDG from cleaning or synthesis solutions. solutions may contain acetonitrle, ether anddehydrated alcohol. no more 0.04% acetonitrle, and less than 0.5% of ether or ethanol FDG QC Sterility - ✔✔ not performed before dosing due to need of 14 days to perform. Regulations require final produce to be placed in soy broth mixture with a thioglycollate growth media for 30 hrs. look for observable bacteria FDG QC Filter membrane integerity - ✔✔ final sterility filter u sed at end of manufacturing process. Filter must remain intact as pressure increased to 50 psi (bubble point test) FDG synthesis room requirements - ✔✔ room: cGMP, ISO class 5 clean room air hood, 21 CFR 212 for manufacturing of IV drugs which radiouclide s are possible radioactive contaminates in eluent of Rb82 generators - ✔✔ Sr82 and Dr85 negative ion PET cyclotrons accelerate which partiles - ✔✔ negatively charged hydrogen atoms chemical method used to label F18 to glucose - ✔✔ nucleophilic substitution

The benefits of buying summaries with Stuvia:

Guaranteed quality through customer reviews

Guaranteed quality through customer reviews

Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.

Quick and easy check-out

Quick and easy check-out

You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.

Focus on what matters

Focus on what matters

Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!

Frequently asked questions

What do I get when I buy this document?

You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.

Satisfaction guarantee: how does it work?

Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.

Who am I buying these notes from?

Stuvia is a marketplace, so you are not buying this document from us, but from seller NurseEdwin. Stuvia facilitates payment to the seller.

Will I be stuck with a subscription?

No, you only buy these notes for $19.49. You're not tied to anything after your purchase.

Can Stuvia be trusted?

4.6 stars on Google & Trustpilot (+1000 reviews)

79650 documents were sold in the last 30 days

Founded in 2010, the go-to place to buy study notes for 14 years now

Start selling
$19.49
  • (0)
  Add to cart