TEST BANK
Rau’s Respiratory Care Pharmacology
10th Edition Gardenhire , Chapters 1 - 23
,Table of Contents
Unit I: Basic Concepts and Principles in Pharmacology
1. Introduction to Respiratory Care Pharmacology
2. Principles of Drug Action
3. Administration of Aerosolized Agents
4. Calculating Drug Doses
5. The Central and Peripheral Nervous Systems
Unit II: Drugs Used to Treat the Respiratory System
6. Adrenergic (Sympathomimetic) Bronchodilators
7. Anticholinergic (Parasympatholytic) Bronchodilators
8. Xanthines
9. Mucus-Controlling Drug Therapy
10. Surfactant Agents
11. Corticosteriods in Respiratory Care
12. Nonsteroidal Antiasthma Agents
13. Aerosolized Antiinfective Agents
14. Antimicrobial Agents
15. Cold and Cough Agents
16. Selected Agents of Pulmonary Value
17. Neonatal and Pediatric Aerosolized Drug Therapy
Unit III: Critical Care, Cardiovascular, and Polysomnography Agents
18. Skeletal Muscle Relaxants (Neuromuscular Blocking Agents)
19. Diuretic Agents
20. Drugs Affecting the Central Nervous System
21. Vasopressors, Inotropes, and Antiarrythmic Agents
22. Drugs Affecting Circulation: Antihypertensives, Antianginals, Antithrombotics
23. Sleep and Sleep Pharmacology
,Chapter 01: Introduction to Respiratory Care Pharmacology Gardenhire:
Rau’s Respiratory Care Pharmacology, 10th Edition
MULTIPLE CHOICE
1. What is the name of the receptor sites that are located in the peripheral vasculature, the heart, bronchial
muscle, and bronchial blood vessels?
a. Beta 2 receptors c. Alpha receptors
b. Gamma receptors d. Beta 1 receptors
CORRECT ANSWER: C
Alpha receptors are located in the peripheral vasculature, the heart, bronchial muscle, and bronchial blood
vessels.
PTS: 1
2. Which receptor site results in tachycardia, an increased potential for arrhythmias, and an increased
cardiac output?
a. Beta 1 receptor c. Alpha receptor
b. Beta 2 receptor d. Delta receptor
CORRECT ANSWER: A
Stimulation of the beta-1 receptors results in tachycardia, an increased potential for arrhythmias, and an
increased cardiac output. In administering drugs to the pulmonary system, stimulation of the beta-1 sites is
not desired. However, most respiratory pharmacologic agents have some beta-1 stimulatory effect.
PTS: 1
3. Stimulation of the beta 2 receptors causes
a. peripheral vasoconstriction and mild bronchoconstriction in the lungs.
b. tachycardia, an increased potential for arrhythmias, and an increased cardiac output.
c. bronchodilation.
d. peripheral vasodilation, bradycardia, and decreased cardiac output.
CORRECT ANSWER: C
Stimulation of the beta-2 receptors in the lungs causes bronchodilation.
PTS: 1
4. Acetylcholine stimulates
, a. the Vagus nerve.
b. the adrenergic receptors.
c. the sympathetic nervous system.
d. the cholinergic receptors.
CORRECT ANSWER: D
Acetylcholine stimulates the cholinergic receptors.
PTS: 1
5. What immunoglobulin antibody sensitizes the mast cell?
a. Leukotrienes c. Histamine
, b. IgE d. Prostaglandins
CORRECT ANSWER: B
The IgE (reagin) antibodies sensitize the mast cell. Repeated exposure to the antigen causes the
degranulation of the mast cell.
PTS: 1
6. Which of the following is caused by histamine release from the mast cells?
I. Bronchodilation
II. Increased bronchial gland secretion
III. Increased amount of mucus present in the airways
a. I and II only c. III only
b. II and III only d. I, II, III
CORRECT ANSWER: B
Histamine is also a potent bronchoconstrictor. In addition to its bronchoconstrictive activity, histamine
II) increases bronchial gland secretion, causing III) an increase in the amount of mucus present
in the airways. Histamine may also have an effect on vascular permeability similar to the effect of-
SRS-A.
PTS: 1
7. A sympathomimetic drug would cause
a. bronchodilation. c. Histamine release.
b. bronchoconstriction. d. Vagus nerve stimulation.
CORRECT ANSWER: A
A sympathomimetic drug would cause bronchodilation. Sympathomimetic agents are the drugs most commonly
used to reverse bronchospasm.
PTS: 1
8. Stimulation of the sympathetic nervous system causes
a. vascular permeability. c. bronchodilation.
b. decreased blood pressure. d. bronchoconstriction.
CORRECT ANSWER: C
Sympathetic nervous system stimulation causes bronchodilation.
PTS: 1
, 9. Which of the following would NOT cause a bronchospasm or bronchoconstriction?
a. Leukotrienes c. Histamine
b. Beta 1 receptors d. Prostaglandins
CORRECT ANSWER: B
Beta-1 receptors would not cause a bronchospasm or bronchoconstriction. Leukotrienes are one of
many chemical mediators released by the mast cells. Leukotrienes cause a direct, strong
bronchoconstriction. Histamine is also a potent bronchoconstrictor. Prostaglandins cause a strong
bronchospasm, especially in asthmatic patients.
PTS: 1
