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Quiz
1
Pharmacology
5334
PCN
drug-drug
interactions
-
ANS
-aminoglycosides
-bacteriostatic
antibiotics
-probenecid
Cephalosporin
Generation
1
-
ANS
-cephalexin
-cephazolin
-cephadoxil
Cephalosporin
and
PCN
-
ANS
Cross
allergy
w/PCN
Carbapenems
-
ANS
not
active
against
MRSA
Vancomycin
treats
-
ANS
gram
positive
Vancomycin
AE
-
ANS
ototoxicity,
nephrotoxicity,
red
man
syndrome
Vancomycin
main
danger
-
ANS
Hosp/vent.
pneumonia
in
pt
w/
Crcl
less
than
50
as
it
increases
mortality
Monobactams
treats
-
ANS
gram
negative
aerobic
Fosfomycin
treats
-
ANS
enterococcus
and
Ecoli
Aminoglycosides
treat
-
ANS
gram
negative
bacilli
Aminoglycosides
adverse
effects
-
ANS
ototoxicity
and
nephrotoxicity
aminoglycosides
peak
and
trough
-
ANS
Peak:
30
min
after
IV
or
IM
Trough:
divided-
before
next
dose,
daily-1
hr
before
next
dose
(value
should
be
low:
like
zero)
Sulfonamides
MOA
-
ANS
inhibit
folic
acid
synthesis
UTI
drugs
-
ANS
1)
TMP/SMZ
and
nitrofurantoin
2)
levofloxacin
&
ciprofloxacin
UTI
in
pregnancy
-
ANS
TMP/SMZ,
Cipro,
Levo,
augmentin,
cephalexin
recurrent
UTI
prophylaxis
-
ANS
TMP
Recurrent
UTI
other
tx
-
ANS
SMZ
3
x
week
for
6
months;
TMP
or
nitro
at
bedtime
for
6
mos. Acute
Bact
Prostatitis
Tx
-
ANS
Floxacins
Tetracycline
adverse
effects
-
ANS
-Yellow/brown
discoloration
of
teeth
-hepatotoxicity
-photosensitivity
-GI
-suprainfection/superinfection
tetracycline
absorption
is
impaired
by
-
ANS
-magnesium
laxative
-antacids
-Calcium
-iron
sup.
-milk
tetracycline
treats
-
ANS
-lyme
dx
-anthrax
-helicobacter
pylori
-mycoplasma
Linezolid
treats
-
ANS
VRE
and
MRSA
Telithromycin
BBW
-
ANS
muscle
weakness
w/myasthenia
gravis
Dalfopristin/Quinupristin
BBW
-
ANS
reserve
only
for
infection
when
not
responding
to
vanco.
to
delay
resistance
Chloramphenicol
BBW
-
ANS
fatal
aplastic
anemia
Retapamulin
and
mupirocin
tx
-
ANS
topical
treatment
for
impetigo
Mupirocin
(topical)
-
ANS
MRSA
in
nostrils
TB
treatment
-
ANS
RIPE
(rifampin,
isoniazid,
pyrazinamide,
ethambutol);
rifapentine
and
rifabutin
TB
treatment
is
effective
when
-
ANS
no
mycobacteria
in
sputum
and
no
colonies
present
in
culture
TB
second
line
injection
drugs
-
ANS
Amikacin
&
Capreomycin
MDR-TB
-
ANS
resistant
to
isoniazid
and
rifampin
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