McCuistion: Pharmacology: A Patient-Centered Nursing Process Approach,
11th Edition
MULTIPLE CHOICE
1. A patient who has traveled to an area with prevalent malaria has chills, fever, and
diaphoresis. The nurse recognizes this as which phase of malarial infection?
a. Erythrocytic phase
b. Incubation phase
c. Prodromal phase
d. Tissue phase
ANS: A
The erythrocytic phase of malarial infection occurs when the parasite invades the red
blood cells and is characterized by chills, fever, and sweating.
DIF: Cognitive Level: Remembering (Knowledge) TOP: Nursing
Process: Assessment MSC: NCLEX: Physiological Integrity:
Pathophysiology
2. A patient is preparing to travel to a country with prevalent malaria. To prevent
contracting the disease, the provider has ordered chloroquine HCl. The nurse will instruct
the patient to take this drug according to which schedule?
a. 500 mg weekly beginning 2 weeks prior to travel and continuing for 8 weeks after
travel.
b. 1000 mg weekly beginning 2 weeks prior to travel and continuing for 8 weeks
after travel.
c. 500 mg once followed by 500 mg per dose in 6 hours, 24 hours, and 48 hours.
d. 1000 mg once daily for 2 days followed by 500 mg daily for 2 to 3 weeks.
ANS: A
For malaria prophylaxis, chloroquine is started 2 weeks before entering an endemic
area and then continued for 8 weeks after leaving the area. The dose is 500 mg
weekly.
DIF: Cognitive Level: Remembering (Knowledge) TOP: Nursing
Process: Planning MSC: NCLEX: Physiological Integrity:
Pharmacological and Parenteral Therapies
3. A patient is taking chloroquine to treat acute malaria. Which statement by the patient
indicates understanding of this medication?
, a. “I should abstain from alcohol while taking this medication because the
combination will make me violently ill.”
b. “I will have to take this medication indefinitely to avoid recurrence of my
infection.”
c. “I should report visual changes immediately.”
d. “I should take this drug on an empty stomach.”
ANS: C
Patients taking chloroquine should report any visual changes or symptoms to the
provider. One does not need to abstain from alcohol, but if the patient drinks large
amounts of alcohol or has a liver disorder, the liver enzymes will require closer
monitoring. Chloroquine is not associated with disulfiram-like reactions. The patient
will likely need to be on therapy for 2-3 weeks, not indefinitely.
DIF: Cognitive Level: Applying (Application) TOP: Nursing Process:
Nursing Intervention: Patient Teaching MSC: NCLEX:
Physiological Integrity: Pharmacological and Parenteral Therapies
4. A patient will take an anthelmintic medication and asks the nurse about common side
effects.
a. The nurse will tell the patient that anthelmintic drugs a. can cause hepatic toxicity.
b. most commonly cause orthostatic hypotension.
c. most commonly result in gastrointestinal (GI) side effects.
d. have many serious adverse reactions.
ANS: C
Anthelmintic drugs have many GI side effects, including anorexia, nausea, vomiting,
diarrhea, and cramps. Adverse reactions do not occur frequently given the short
treatment duration of 1-3 days.
DIF: Cognitive Level: Understanding (Comprehension) TOP: Nursing
Process: Planning MSC: NCLEX: Physiological Integrity:
Pharmacological and Parenteral Therapies
5. A child is being treated for pinworms, and the parent asks the nurse how to prevent
spreading this to other family members. What will the nurse tell the parent?
a. “Give your child baths every day.”
b. “Obtain a daily stool specimen from your child.”
c. “Change sheets, bedclothes, towels and underwear weekly.”
d. “Your child should wash hands well before meals and after using the toilet.”
ANS: D
To prevent the spread of pinworms, good hand washing after toileting is
recommended. Patients should take showers, not baths. It is not necessary to get
regular stool specimens. Sheets, bedclothes, towels and underwear should ideally be
changed daily.
6. A child is prescribed pyrantel pamoate. The nurse understands that this is most likely
prescribed to treat which condition?
a. Candidiasis
b. Schistosomiasis
c. Pinworms
d. Liver flukes
ANS: C
Pyrantel pamoate is used to treat pinworms. Schistosomiasis and liver flukes are
better treated with other anthelmintic products indicated to treat these conditions.
Candidiasis would be treated with an antifungal agent.
DIF: Cognitive Level: Applying (Application) TOP: Nursing Process:
Nursing Intervention: Patient Teaching MSC: NCLEX:
Physiological Integrity: Pharmacological and Parenteral Therapies
7. The nurse is preparing to administer an intravenous polymyxin antibiotic. The patient
reports dizziness along with numbness and tingling of the hands and feet. The nurse will
perform which action?
a. Administer the drug since these are harmless side effects.
b. Hold the drug and notify the provider of these adverse reactions.
c. Obtain an order for an oral form of this medication.
d. Request an order for serum electrolytes.
ANS: B
Polymyxins can cause nephrotoxicity and neurotoxicity. This patient has signs of
neurotoxicity, so the nurse should notify the provider. These effects are generally
reversible when the drug is discontinued. It is not correct to administer the drug when
these symptoms are present.
Polymyxins are not absorbed orally. Serum electrolytes are not indicated.
DIF: Cognitive Level: Applying (Application) TOP: Nursing Process:
Nursing Intervention MSC: NCLEX: Physiological Integrity:
Pharmacological and Parenteral Therapies
8. A young adult female is prescribed metronidazole to treat trichomoniasis. Which of the
following is FALSE regarding metronidazole?
a. Metronidazole is not appropriate for this patient because it is only indicated for
bacterial infections.
b. Alcohol use is contraindicated.
c. Metronidazole is available in multiple dosage forms, including oral, topical,
intravaginal, and IV products.
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