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PSYC3604 Lecture 9 Schizophrenia and Psychotic Disorders

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Schizophrenia Spectrum and Other Psychotic Disorders - Psychotic disorders: characterized by unusual thinking, distorted perceptions, and odd behaviours o Impaired reality o Inability to think coherently o Some long lasting, others temporary - Psychosis: a severe mental condition characterize...

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PSYC3604 Lecture 9
Schizophrenia and Psychotic Disorders

PSYC 3604 Final Exam

PSYC3604 Lecture 9
Schizophrenia and Psychotic Disorders

Schizophrenia Spectrum and Other Psychotic Disorders
- Psychotic disorders: characterized by unusual thinking, distorted perceptions, and odd
behaviours
o Impaired reality
o Inability to think coherently
o Some long lasting, others temporary
- Psychosis: a severe mental condition characterized by a loss of contact with reality
o Delusion: a false belief
o Hallucination: a false sensory perception
o Both at the same time
o Loss of contact with reality
o Presence of them does not mean psychotic disorder
o Can occur in brain tumors, brain trauma, or exposure to toxic chemicals
o Voices as negative and upset by them and lack of control

What are the schizophrenia spectrum and other psychotic disorders?
- Abnormalities in 1 or more of 5 domains including delusions, hallucinations,
disorganized thinking or behaviour, and negative symptoms
- Includes…
o Schizophrenia
o Schizophreniform disorder
o Schizoaffective disorder
o Delusional disorder
o Brief psychotic disorder
o Substance/medication-induced psychotic disorder
o Psychotic disorder due to another medical condition
o Other specified schizophrenia spectrum and other psychotic disorder
o Unspecified schizophrenia spectrum and other psychotic disorder
- Schizotypal personality disorders considered apart of these disorders, but in DSM5 =
other personality disorders
- Lose contact with reality
- Schizophrenia = most severe psychopathology in this class

Movies
- Portrayed as violent

Early descriptions of schizophrenia
- Emil Kraepelin  first formulated in 1800s

,PSYC3604 Lecture 9
Schizophrenia and Psychotic Disorders

o Dementia praecox 
o Early onset and intellectual deterioration
o Defining features = disturbances perceptions in perceptual and cognitive faculties
- Eugen Bleuler
o Schizophrenia meaning split mind
o Disturbances caused by associative splitting
o Renamed it schizophrenia
o Did not believe in early onset
o Did not believe in progress towards dementia
o Phren = mind
o Tried to specify common denominator  breaking of associative threads (core)
 Words and thoughts
o 4 core symptoms
 Ambivalence, disturbance of affect and association, preference for fantasy
over reality

Misconceptions about schizophrenia
- Common myths
o Split personalities  split = between thoughts and feelings, not personality
o Multiple personalities  compared to DID (2+ personalities each with own
thoughts, feelings, and behaviours)
o Violent  rates of violence are no higher among people with other disorders
 Rarely serious, perpetrated by someone with comorbid substance use
disorder
- Still not as well understood
- Inability to perceive environment appropriately

What is schizophrenia
- Schizophrenia: a severe psychological disorder characterized by disorganization in
thought, perception, and behaviour
- Ideas are not logically related
- Incapable of logical thought
- Flat or inappropriate affect
- Impaired motor activity
- Considerable variability in this disorder from person to person
- Symptoms of schizophrenia
o Positive symptoms  group of symptoms including unusual thoughts, feelings,
and behaviours
 Too much of a behaviour not apparent among most people
 Excess or distortions
o Negative symptoms  absence of a behaviour that should be in most people
 Behaviourial deficits
- Some use 3 dimensions  disorganized symptoms

,PSYC3604 Lecture 9
Schizophrenia and Psychotic Disorders

o Rambling speech, erratic behaviour, inappropriate affect (disorganized within
positive)
- Onset  late adolescence or early adulthood
o Early vs. intermediate vs. late onset
o Abrupt or gradual
o Early = before 19  risk for lifelong disorder
o Socially withdrawn
o Long time before actively showing psychotic symptoms
- Course
o Prodromal phase  before onset
 Extended period of time before full onset
 Unusual, less severe
 Impairments
 Social withdrawal, isolation, deterioration in personal hygiene, difficulty
functioning in school or work
 Ideas of reference, magical thinking, delusions (feeling presence)
 1-2 years, can take upwards of 10 years before meeting full criteria
o Acute phase  positive symptoms emerge
 Psychotic symptoms more noticeable
o Residual phase
 Positive symptoms no longer present, negative may remain
- Epidemiology  prevalence rates average 1% in Canada
o 16-40 of every 100,000 people develop
o More common in males
o 1% of population
o 0.3 – 1.6% in US
o Higher in certain urban settings
o Gender difference may be due to diagnostic criteria
- Comorbidity  common – mood disorders, anxiety disorder, PTSD, substance use,
personality disorders
o Major depressive disorder (40%)  violence, arrests, victimization
o 47% have anxiety  social anxiety = common
o 43% have PTSD
o Up to 80% have history of substance abuse in lifetime
o Commonly abuse alcohol or cannabis  poor recovery
o Self-medication hypothesis to relieve negative symptoms
o Personality disorder  avoidant, antisocial, paranoid, dependent
- Functional impairment
o One of the top 10 most debilitating conditions in the world
o Symptom severity equals the level of impairment
o Correlation between severity and impairment
o Self-care, independent living, relationships, work, school = impairment
o Strange behaviour and social skills deficits = less connections

, PSYC3604 Lecture 9
Schizophrenia and Psychotic Disorders

o Overrepresented in jails and homeless shelters
o Significant human toll on the individual and family  poor quality of life
o Personal care and independent living
o Interpersonal relationships
o Work and school
o Substance abuse
- Mortality  decreased life expectancy of 10-20 years
o 3x risk of death  drug use, lower family involvement, side effects of medication
o High risk of suicide
 10% die by suicide
 40-60% attempt
- Prognosis  poorer than other disorders
o A number of acute episodes
o Chronic, relapse is common
o Chronic for 57%
o 39% have intermittent
o Only 1 in 3 achieve remission  milder symptoms, shorter duration of psychosis
o Symptom severity, treatment response, and comorbidity impact outcomes
o Early treatment is important
o Comorbidity increases poor outcome
o Many remain chronically disabled
- Sex, race, ethnicity
o Gender differences in schizophrenia
 Higher in men 4:1 ratio
 Women develop later, milder forms, better social functioning
 Later age of onset for women = more positive outcomes, developmental
milestones, better social functioning
 Estrogen may be protective factor
 Socialized to be more socially competent
o Symptoms common across racial and ethnic groups
o Cultural differences in outcomes
o Developmental factors, including early signs or symptoms
o Higher in African Americans or immigrant minority groups
o Hallucinations higher in African American populations
o Differing rates may reflect diagnosis
o Outcome varies from culture to culture
 Positive in developing countries rather than developed
 Developed place more importance on independence
 Developing place emphasis on family, community, and social support
- Developmental factors
o Early signs or symptoms
 Delusional experiences 
 Lower sociability 

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