OpenStax Microbiology Test Bank Chapter 14: Antimicrobial Drugs
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OpenStax Microbiology
Institution
OpenStax Microbiology
OpenStax Microbiology Test Bank Chapter 14: Antimicrobial Drugs
* = Correct answer Multiple Choice
1. Which was the first antimicrobial agent discovered to treat syphilis?
A. chloramphenicol
B. compound 606*
C. penicillin
D. sulfonamide
2. Who is credited for first finding an antim...
OpenStax Microbiology Test Bank Chapter 14:
Antimicrobial Drugs
* = Correct answer
Multiple Choice
1. Which was the first antimicrobial agent discovered to treat syphilis?
A. chloramphenicol
B. compound 606*
C. penicillin
D. sulfonamide
2. Who is credited for first finding an antimicrobial agent?
A. Paul Ehrlich*
B. Alexander Fleming
C. Edward Jenner
D. Joseph Lister
3. Who is credited for first finding a naturally occurring antimicrobial agent?
A. Paul Ehrlich
B. Alexander Fleming*
C. Edward Jenner
D. Joseph Lister
4. Alexander Fleming first observed a mold (now known as Penicillium notatum) that was able
to inhibit which organism?
A. Escherichia
B. Listeria
C. Staphylococcus*
D. Streptococcus
5. Which of the following is a semisynthetic antimicrobial agent?
A. actinomycin
B. ampicillin*
C. streptomycin
D. neomycin
6. Which describes the difference between a secondary infection and a superinfection?
A. A secondary infection is a type of superinfection that develops when antibiotics are
not given.
B. A superinfection is a type of secondary infection that can develop when antibiotics kill
much of the patient’s normal flora.*
C. A superinfection is a type of secondary infection that develops when antibiotics taken to
treat a particular pathogen do not completely kill all of that original pathogen.
D. A secondary infection is a type of superinfection that develops when the pathogen
, mutates in response to the antimicrobial agent.
7. Life-threatening diseases caused by bacterial pathogens should be treated with which of the
following?
A. bactericidal agents only*
B. bacteriostatic agents only
C. both bacteriostatic and bactericidal agents.
D. neither bacteriostatic nor bactericidal agents
8. Which of the following is a -lactam antibiotic?
A.*
B.
C.
TESTBANKSELLER.COM
, 9. Which of the following is not a -lactam antibiotic?
A. carbapenem
B. cephalosporin
C. penicillin
D. tetracycline*
10. How does penicillin work?
A. Penicillin binds to penicillin-binding proteins, thus inhibiting the
transglycosylation reaction during cell wall synthesis.
B. Penicillin binds to penicillin-binding proteins, thus inhibiting the transpeptidation
reaction during cell wall synthesis.*
C. Penicillin blocks the movement of peptidoglycan subunits from the cytoplasm to
the exterior of the cell.
D. Penicillin inserts into the plasma membrane, causing cell lysis.
11. How does bacitracin work?
A. Bacitracin binds to penicillin-binding proteins, thus inhibiting the transglycosylation
reaction during cell wall synthesis.
B. Bacitracin binds to penicillin-binding proteins, thus inhibiting the transpeptidation
reaction during cell wall synthesis.
C. Bacitracin blocks the movement of peptidoglycan subunits from the cytoplasm to
the exterior of the cell.*
D. Bacitracin inserts into the plasma membrane, causing cell lysis.
12. The penicillins act on which typed of bacteria.
A. gram-negative bacteria only
B. gram-positive bacteria only
C. mostly gram-negative bacteria and some gram-positive bacteria
D. mostly gram-positive bacteria and some gram-negative bacteria*
13. The aminoglycosides directly target which structure of the bacterial cell?
A. 30S ribosomal subunit*
B. 50S ribosomal subunit
C. cell wall
D. plasma membrane
14. The macrolides target which feature of the bacterial cell?
A. 30S ribosomal subunit
B. 50S ribosomal subunit*
C. cell wall
D. plasma membrane
E.
15. Which of the following was the first broad-spectrum antibiotic to be approved by the FDA?
A. chloramphenicol*
B. compound 606
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