WGU
Pathophysiology
D236
Describe
how
your
body
responds
to
an
infection.
-
ANST
cells
produce
cytokines,
which
stimulate
B
cells.
B
cells
produce
antibodies.
Identify
role
of
DNA
changes
in
congenital
abnormalities.
-
ANSMutations
in
genes
or
chromosomal
abnormalities
How
does
development
disrupts
congenital
abnormalities?
-
ANSAlterations
of
DNA
Describes
factors
that
disrupt
homeostasis
and
how
disruptions
affect
wellbeing.
-
ANS(ex)
Fluid
and
electrolyte
shifts
can
cause
n/v
or
dysrhythmias.
Explain
RAAS
-
ANSRenin-angiotensin-aldosterone
system
1.
Reduce
blood
flow
causes
kidneys
to
release
renin
>
produce
angiotensin
I
>
converts
angiotensin
I
to
angiotensin
II
>
vasoconstriction
>
release
aldosterone
>
kidneys
conserve
sodium
and
water
>
Result
less
water
lost
in
urine
and
blood
pressure
maintained.
DKA
-
ANSincreased
anion
gap,
decreased
HCO3
How
do
kidneys
compensate
for
alkalosis
-
ANSretain
H
and
excrete
HCO3
Untreated
acidosis
leads
to
an
increase
in
which
electrolyte?
-
ANSPotassium
West
Nile
Virus
-
ANSTransmitted
through
the
bite
of
an
infected
mosquito.
Severe
signs
and
symptoms;
high
fever,
headache
and
stiff
neck
Lyme
disease
-
ANSTick-borne
disease
caused
by
the
spirochete
Borrelia
burgdorferi.
Erythema
infectiosum
-
ANSa
febrile
upper
respiratory
illness
in
a
child
followed
by
the
sudden
appearance
of
red,
flushed
cheeks,
"fifth
disease"
Obesity
ad
diabetes
are
risk
factors
for
having
a
child
with
_____.
-
ANSSpina
bifida
Trousseau's
sign
-
ANSarm/carpal
spasm
associated
with
hypocalcemia
Cause
and
sign
of
spina
bifida
-
ANSresults
from
failure
of
neural
tube
to
close.
sign
-
fluid
filled
sac
on
lower
back.
hemophilia
is
more
common
in
-
ANSmales
Prenatal
exposure
to
alcohol
includes
-
ANSND-PAE,
decreased
brain
function,
FAS
Connective
vs
muscle
tissue
disorders
-
ANSConnective-
RA,
Scleroderma,
Lupus Muscle
-
MS,
Muscular
dystrophy,
Myasthenia
Gravia
Describe
Lupus
-
ANSInflammatory
disorder
characterized
by
joint
pain
and
butterfly
rash
Describe
Myasthenia
Gravis
-
ANSIt
is
an
autoimmune
disorder
where
antibodies
attack
own
Ach
receptors.
This
causes
weakness
of
skeletal
muscles
over
the
course
of
the
day,
along
with
ptosis,
double
vision,
and
difficulty
swallowing.
dermatitis
-
ANSinflammation
of
the
skin
eczema
-
ANSnoninfectious,
inflammatory
skin
disease
characterized
by
redness,
blisters,
scabs,
and
itching
decubitus
ulcer
-
ANSsore
caused
by
lying
down
for
long
periods
of
time
Fungal
infections
-
ANSsuperficial,
localized
skin
conditions
or
deep
tissue
infections
caused
by
exposure
to
spores
may
or
may
not
be
transmitted
benign
neoplasm
-
ANSnoncancerous
growths,
stationary,
distinct
borders
malignant
neoplasm
-
ANSuncontrolled
new
tissue
growth,
irregular
borders,
spreads
Osteoporosis
-
ANSThe
loss
of
bone
mass
often
due
to
age,
causing
the
bones
to
become
porous,
brittle,
and
easily
fractured.
osteomalacia
-
ANSdisease
marked
by
softening
of
the
bone
caused
by
calcium
and
vitamin
D
deficiency
myoglobin
-
ANSred
pigment
that
stores
oxygen
in
muscle
cells
Bursa
-
ANSfluid-filled
sac
that
allows
for
easy
movement
of
one
part
of
a
joint
over
another
Rickets
-
ANSa
vitamin
D
deficiency
in
children,
resulting
in
soft
bones
Degenerative
disk
disease
-
ANSA
condition
in
which
an
intervertebral
disk
loses
its
normal
structural
integrity
as
a
result
of
wear
and
tear,
acute
or
repeated
injuries
or
aging
Paget
disease
-
ANSChronic
inflammation
of
bones,
resulting
in
thickening
and
softening
of
bones,
that
can
occur
in
any
bone
but
most
commonly
affects
the
long
bones
of
the
legs,
the
lower
spine,
the
pelvis,
and
the
skull
communiuted
fracture
-
ANSsplintered
into
many
pieces
Three
types
of
skin
cancer
-
ANS1.
Basal
cell
carcinoma
2.
Squamous
cell
carcinoma
3.
Melanoma
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