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Summary Miscarriage

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A 1-4 page document written by a final year medical student with distinction grades in the uploaded modules. These notes are concise and of very high quality - using a combination of textbooks, lectures, and current guidelines (NICE and RCOG). These documents are the only resource you should need f...

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  • December 19, 2018
  • 3
  • 2017/2018
  • Summary
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Miscarriage
 Miscarriage = Loss of a recognised IUP before 24 weeks gestaton (i.e. before it is capable of independent
survival, afer which it is known as a ‘stllbirth’/IUFD)
- Early miscarriage (80%) - frst triiester i.e. <12 weeks
o Most likely chromosomal.
o Death of eibryo/foetus before expulsion
- Late miscarriage (20%) - second triiester i.e. week 12-24
o More likely anatomical factors.
o Death of foetus after expulsion.

Epideiiology
 15-20% of all known pregnancies iiscarriage
 If you’ve had one, the next one is slightly iore likely (~23%)
 50-75% of all pregnancies (known and unknown) abort spontaneously, iost unrecognised as it occurs
before/at tie of next ienses

Classifcaton/teriinology of Spontaneous Miscarriage
 Threatened miscarriage = Os closed, ieibranes intact  Viable
- ANY PV bleeding (+/- pain) before 24 weeks
- 50% will iiscarry (although lower risk if foetal heart beat seen)
- Those who don’t iiscarry have high risks of preteri delivery, low birthweight, and perinatal death.
 Missed miscarriage = Os closed, lack of norial IUP notced at next antenatal scan  Non-viable
- Asyiptoiatc due to placenta not detaching froi the uterus behind a closed os for days or weeks.
- Later there iay be bleeding and brown vaginal discharge.
 Inevitable miscarriage = Os open, ieibranes ruptured, foetus not yet expelled  Non-viable
 Incomplete miscarriage = Os open, products partally expelled (usually between week 6-14)  Non-viable
 Complete miscarriage = Os closed, products coipletely expelled (usually <6 or >14 weeks)  Non-viable
 Recurrent miscarriage = 3 consecutve iiscarriage (Usually due to APLS. Should be referred for further
investgaton).
 Septic miscarriage = iissed or incoiplete iiscarriage which has becoie infected. Woien present with
fever, leucocytosis, uterine tenderness, and foul-sielling discharge.




Aetology
 Idiopathic
 Foetal factors:
- Chromosomal (50%) - autosoial trisoiies (13, 16, 18, 21, 22), ionosoiies (45X).
- Developmental – abnoriality of zygote, eibryo, early foetus, or even placenta (e.g. blighted ovui –
eibryo never develops or is reabsorbed/degenerated)

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