1. How does the orbitofrontal cortex (OFC) affect the amygdala?
inhibits and activates the amygdala
2. Wernicke's area is associated with which of the following?
speech comprehension
3. The limbic system is associated with which of the following
emotion and learning
4. Which brain structure is most associated with long term memory?
hippocampus
5. When prescribing psychotropic medications, the PMHNP knows that these
medications work within which specific areas?
mood
6. Which of the following are involved in regulating neurotransmission via
excitation-secretion coupling?
voltage-sensitive sodium channels and voltage-sensitive calcium channels
7. What system influences the length of time for a drug to achieve efficacy?
signal transduction cascades
8. One of the signal transduction cascades, pass the message from a first
receptor to a second messenger.
G protein linked systems
,9. Human central nervous system communication at synapses is which of the
following?
chemical
10. Which of the following is an excitatory neurotransmitter?
glutamate
11. Which statement correctly pairs the pharmacodynamic effect with its
definition?
antagonist effect - drug binds to receptor, but does not activate a response
12. A major current hypothesis for the cause of schizophrenia proposes that N-
methyl-d-aspartate (NMDA) receptors may be which of the following?
Correct!
hypofunctional
13. Which medication is least associated with weight gain?
aripiprazole
14. Which dopamine pathway is associated with positive symptoms of
schizophrenia?
mesolimbic pathway
15. Which pathway is associated with negative symptoms?
The mesocortical pathway
16. Is part of the extrapyramidal nervous system and associated with
extrapyramidal symptoms (EPS)
nigrostriatal pathway
17. This pathway is associated with hyperprolactinemia.
, The tuberoinfundibular pathway
18. A 34-year old male recently began experiencing breast secretions while
receiving risperidone . Which dopamine pathway is associated with this
side effect?
tuberoinfundibular pathway
19. A 44-year-old woman is initiated on an atypical antipsychotic for the
treatment of schizophrenia. Regarding affinity, atypical antipsychotics
demonstrate which of the following most often?
Atypical antipsychotics have equal positive symptom antipsychotic actions and low
extrapyramidal symptoms.
20. is a syndrome that can be associated with several different psychiatric
disorders. Symptoms include hallucinations, delusions, disorganized
speech, disorganized behavior, and distortions of reality. This syndrome
can affect a person's cognition, affective response, communication,
capacity to recognize reality, and ability to relate to others.
psychosis
21. What Diagnosis require the presence of psychosis?
schizophrenia
substance-induced psychotic disorders
schizophreniform disorder
schizoaffecive disorder
delusional disorder
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