NURS 6630: Psychopharmalogical Approaches to Treat Psychopathology questions with correct answers
Perphenazine brand name Correct Answer-Trilafon
Perphenazine (Trilafon) Class Correct Answer-First Generation Antipsychotic
Perphenazine FDA indication uses Correct Answer-Schizophrenia
Nausea & Vomiting
Perphenazine mechanism of action Correct Answer-Perphenazine is a piperazinyl phenothiazine that has activity in all levels of the central nervous system, specifically the hypothalamus, although the site and mechanism of action of its therapeutic action are still unknown
Perphenazine (Trilafon) Contraindications Correct Answer-Hypersensitivity to Perphenazine or any other component of the formula Use with large doses of other CNS depressants
Liver damage
Subcortical Brain Damage
Perphenazine dosing for Schizophrenia Correct Answer-Schizophrenia:
Moderately disturbed, Non-hospitalized patient:
Initial dosage: 4mg-8mg orally three times a day.
Maintenance dosage: 8mg-32mg a day given once or twice daily
Hospitalized patient: 8mg - 16mg orally 2 to 4 times a day. Max dose : 64mf/day
The dosage for seniors may be in the 8-16 mg/day range. Perphenazine Side Effects Correct Answer-Common:
mild dizziness, blurred vision, headache, drowsiness,
sleep problems (insomnia), strange dreams, loss of appetite, vomiting, diarrhea, constipation, increased sweating, increased urination, dry mouth, stuffy nose,
breast swelling or discharge, mild itching, and
skin rash
Perphenazine How supplied Correct Answer-Perphenazine (perphenazine) tablets, USP are round, unscored, film-coated white tablets available as:
2mg,4mg,8mg, and 16mg
Perphenazine dosing for Nausea & Vomiting Correct Answer-Recommended dose:
8 to 16 mg orally, in divided doses.
Maximum dose: 24 mg/day, in divided doses
The dose should be reduced as early as possible.
Perphenazine dosing for Pediatric dose for Psychosis Correct Answer-12 years and
older:
Moderately disturbed, Nonhospitalized patients:-Recommended dose: 4 to 8 mg orally 3 times a day, with a dose reduction to the minimum effective dose as soon as possible
Maximum dose: 24 mg/day Hospitalized patients:-Recommended dose: 8 to 16 mg
orally 2 to 4 times a day-Maximum dose: 64 mg/day
Nonhospitalized patients should be limited to a daily dose of 24 mg; maximum doses of 64 mg should be used in hospitalized patients.
Perphenazine dosing for Pediatric dose for Nausea & Vomiting Correct Answer-12
years and older:-
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