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PACOP 2000 PCOL questions with complete solutions
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PACOP 2000 PCOL questions with complete solutions
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PACOP 2000 PCOL questions with completesolutions
1. The driving force for passive absorption of the drug is the:
a. Specific carrier proteins and shoes saturation kinetics
b. Concentration gradient across a membrane separating body compartment
c. Both
d. None Correct Answer-b. Concentration gradient across a membrane
2. Physical factors influencing absorption:
a. Total surface are available for absorption b. Contact time at the absorption surface
c. Blood flow to the absorption site
d. All
e. None Correct Answer-d. All
3. Clinical effectiveness often depends on:
a. Maximum serum drug concentration
b. Minimum serum drug concentration
c. Time after concentration required to reach onset of concentration d. All
e. None Correct Answer-a. Maximum serum drug concentration
4. Process by which drugs find their way into the urine, EXCEPT: a. Active glomerular filtration
b. Active tubular secretion
c. Passive tubular secretion
d. Passive glomerular filtration e. None Correct Answer-a. Active glomerular filtration
5. A drug which has no effect enhances the effect of a second drug:
a. Antagonism
b. Potentiation
c. Synergism
d. Summative
e. Additive Correct Answer-b. Potentiation
6. Parameters used to evaluate time-response relationship, EXCEPT:
a. Duration of action
b. Latency
c. Peak time
d. Onset of action
e. None Correct Answer-e. None
7. When the dose of the drug is gradually increased and all first noticeable effect is observed, the dose that produces this effect is called:
a. Quantal dose b. Threshold dose
c. Lethal dose
d. A and B
e. B and C Correct Answer-b. Threshold dose
8. Regulated and directs sensory impulses traveling to the cortex:
a. Thalamus
b. Pons
c. Medulla
d. Hypothalamus Correct Answer-a. Thalamus
9. Inhaled anaesthetic are relatively insoluble in blood and are eliminated at faster rate than the more soluble anaesthetics:
a. True
b. False Correct Answer-a. True
10. Coordinate body movement and posture to help maintain body
a. Cerebrum
b. Brainstem
c. Cerebellum
d. None Correct Answer-c. Cerebellum
11. Treatment of neuroses:
a. Psychotherapy
b. Anxiolytic
c. Antidepressants d. All
e. None Correct Answer-d. All
12. Used prophylactically in treating manic depressive patients and in the treatment
of manic episodes:
a. Anti-psychotics
b. Lithium salts
c. Anxiolytic drugs
d. All Correct Answer-b. Lithium salts
13. Used in treating complex partial seizure
a. Phenytoin
b. Carbamazepine
c. Both
d. None Correct Answer-c. Both
14. Generalized tonic-clonic drug:
a. Phenobarbital
b. Phenytoin
c. Diazepam
d. Valproic acid Correct Answer-d. Valproic acid
15. The most important criterion in determining whether surgical anesthesia has been achieved is:
a. Papillary dilation
b. Respiratory lagging
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