Chapter 1 Stahl's Essential Psychopharmacology, Complete With Questions and Correct Answers, Updated 2024.
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Stahl\\\'s Essential Psychopharmacology,
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Stahl\\\'s Essential Psychopharmacology,
Chapter 1 Stahl's Essential Psychopharmacology, Complete With Questions and Correct Answers, Updated 2024.
largely the story of chemical neurotransmission
Modern psychopharmacology is
Anatomically, chemically, and electrically
neurotransmission can be described as
Neurons (nerve cells)
Anat...
Chapter 1 Stahl's Essential Psychopharmacology,
Complete With Questions and Correct Answers, Updated
2024.
largely the story of chemical neurotransmission
Modern psychopharmacology is
Anatomically, chemically, and electrically
neurotransmission can be described as
Neurons (nerve cells)
Anatomical neurotransmission occurs through
axoaxonic synapse
synapse between axon of one neuron and axon of another neuron
axodendritic synapse
between axon terminals of one neuron and dendrites of others
axosomatic synapse
axon terminal ends on cell body (soma)
axoaxonic, axodendritic, axosomatic synapses
Axoaxonic- The strongest signal. "The brakes" axon connecting to another axon. They
can increase or decrease the effect of axodendritic signals by opening and closing
Ca2+ channels.
Axodendritic- Most common but also the weakest. Axon connecting to the dendrite of
another cell.
Axosomatic- axon of one cell connecting to the soma of another. Axosomatic is not
selective in inhibition, it will block a signal from all dendrites on the cell where as
axodendritic will only block the effects from one synapse.
neuron malfunction
behavioral symptoms may occur
when drugs alter the neuronal function
behavioral symptoms may be relieved, worsen, or be produced
en passant synapse
axon stimulates a synapse secondarily on its way to another neuron
Serotonin (5HT), Norepinephrine, dopamine, acetylcholine, glutamate, GABA (y-
aminobutyric acid)
Six key neurotransmitter systems
B-endorphin
a neurotransmitter that serves as a natural painkiller
Anandamide
endogenous cannabinoid
The striatum (basal ganglia)
has dopamine reuptake pumps in abundance
basal ganglia function
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