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The LEGO Bricks of Life - Case 8 - Maastricht University - Biomedical Sciences
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This document contains the information for case 8 BBS1001 Maastricht University. Case 8 Ossobuco.
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Case 8: Ossobuco BBS1001 2023/202429 september 2023
Keywords:
- Connective tissue
- Muscle tissue/cell
- Bone marrow
- Tissue types
- Tissue cells
- Organs
- Epithelial tissue
- Collagen
Problem statement:
Different types of tissue in the body.
Epithelium covers the organs.
Brainstorming:
4 types of tissue epithelial tissue, connective tissue, muscle tissue, nerve tissue
Tissue group of cells with the same function.
Types of cells:
- Muscle cell (smooth, skeletal, cardiac muscle)
- Neuron cell
- Epithelial cells (squamous, cuboidal, columnar, transitional)
- Connective tissue
Muscle:
- Voluntary skeletal muscle
- Involuntary cardiac + smooth muscle
Blood mobile connective tissue
Learning goals:
1. What are the cell types? Structure and function
2. What are the tissue types?
3. Structure and function neuron (short)
4. Types of muscle tissue. Structure and function.
5. What is connective tissue? Cells and fibers.
6. What are other types of tissue you can find in the muscle?
, Case 8: Ossobuco
1. What are the cell types? Structure and function
Epithelial cell
Where to find:
- Skin
- Respiratory system
- Reproductive system
- Urinary system
- Circulatory system
- Gastrointestinal system
Epithelial cells are usually characterized by the presence of a large nucleus and a polar
arrangement. That is, they have a defined structural orientation, with the membranes on
either side possessing a distinct set of proteins.
Epithelial cells form epithelial tissues which line the surface of organs. Epithelial cells are
usually tightly packed, resulting in ‘cell-rich’ tissue with very little extracellular space
between them. They form uniform sheets of cells, often in layers. Despite these similarities,
epithelial cells are diverse, and the resulting tissues are variable. This diversity allows them
to perform a range of functions.
There are many different types of epithelial cells. They are usually classified in two ways, by
their shape and by their formation of layers. In terms of shape, epithelial cells can be
categorized as squamous, columnar, or cuboidal. Epithelial tissue can be further divided into
‘simple’, where there is only one layer of cells, or ‘stratified’, where there is more than one
layer of cells.
Not all the layers of cells have to be of one particular type for the tissue to be considered a
stratified epithelium. Some of the deeper layers may contain cells of different shapes. For
example, a stratified squamous epithelium could have columnar or cuboidal cells at the
deeper layers of the tissue.
Squamous epithelial cells
Simple squamous epithelium:
- This type is leaky and therefore enables materials to pass through
it quite easily.
- Lines in the blood vessels, some cells of the lungs, and the heart.
Stratified squamous epithelium:
- Is associated with rapid regeneration by cell division; outer layers
can be ‘sloughed’ off and replaced by new cells.
- Lines in outer layer of the skin, mouth, esophagus, vagina, and
anus.
Columnar epithelial cells
Simple columnar epithelium:
- Most often associated with producing secretions and are therefore found lining the
cells of the gastrointestinal tract.
- There are also sub-types that are ciliated. (trilhaartjes) these cells feature an
arrangement of hair-like structures on their surface that act to move mucus down a
tract.
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