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BIOD 210 Module 5 Exam Genetics - Portage Learning
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BIOD 210 Module 5 Exam Genetics - Portage Learning
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By: Fordenken • 4 months ago
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BMSC 210 Module 5 - Bacterial Genetics1. Why are wild type genotypes useful?: They are used as a non-mutated
reference point
2. Screening tests hundreds/thousands/millions of colonies (select one): -
Thousands
3. What are auxoautotrophs?: Mutants that cannot biosynthesize certain amino
acids
4. What is a spontaneous mutation?: A mutation that arises naturally and not
as a result of exposure to mutagens
5. What is an induced mutation?: Caused by mutagens
6. What is a point mutation?: Substitution, deletion, or insertion of a single
base pair
7. What is a silent mutation?: Often a base change in 3rd position of codon,
that doesn't actually effect the amino acid that is coded for (tRNA wobble)
8. What is a missense mutation?: A point mutation, usually in the first or
second position, that changes the amino acid that is coded for
9. What is a nonsense mutation?: A point mutation that results in the code
being turned into a stop codon, which then results in an incomplete/truncated
protein
10. What is an indel mutation?: An insertion or deletion
11. What is a frameshift mutation?: Mutation that shifts the "reading" frame of
the genetic message by inserting or deleting a nucleotide
12. What is a reversion?: When a second mutation cancels the effect of the first
one. There are several different types of this mutation
13. Revertant mutation: Type of reversion. When the phenotype is returned to
the wild type
14. True revertant mutation: When the genotype is returned to the wild type
genotype
15. Suppressors and types: Suppress mutations
- Can be the same gene, but different location, that still restores protein activity
- Can be on a different gene, that then restores the function of the original gene
- Can be on a different gene that compensates for or replaces the original gene
16. The error rate for spontaneous mutation is 1 in ___________: 10 million/s
17. Nucleotide base analog: Type of mutagen that resembles a nucleotide, and
is inserted during replication. Leads to faulty base paring, and a high error rate at
the point of insertion
18. Chemical modification: Type of mutagen that modifies one of the bases,
which results in faulty base pairing. This mutagen does not require replication to
first occur 19. Intercalating agents: Type of mutagen that inserts between two
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