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TEST BANK FOR MODERN BLOOD BANKING & TRANSFUSION PRACTICES 6TH EDITION DENISE M. HARMENING |ALL CHAPTERS COVERED (RATED A+)
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TEST BANK FOR MODERN BLOOD BANKING & TRANSFUSION PRACTICES 6TH EDITION DENISE M. HARMENING |ALL CHAPTERS COVERED (RATED A+) This study source was downloaded by 100000826342158 from CourseHero.com on 09 -15-2021 17:54:15 GMT -05:00 https://www.coursehero.com/file/25537437/ch01rtf/ Chapter 1 RBCs and Platelet Preservation: Historical Perspectives and Current Trends Multiple Choice Identify the choice that best completes the statement or answers the question. 1. Which metabolic pathway is responsible for generating 90% of the ATP for the RBC? a. Pentose phosp hate shunt c. Glycolysis b. Luebering -Rapoport shunt d. Methemoglobin reductase 2. A unit of blood was returned to the blood bank before it was spiked. Apparently the patient’s IV failed. The unit of blood was outside the blood bank for 35 minutes. Which of the statements below is most accurate? a. The unit of blood should be discarded immediately. b. The unit of blood can be returned to inventory. c. The unit of blood must be transfused within 4 hours or be discarded at the end of that time. d. The unit of blood must be transfused with 24 hours. 3. What is the average diameter of a platelet? a. 5 to 10 µm c. 1 to 2 µm b. 2 to 4 µm d. 4 to 6 µm 4. In the normal hemoglobin -oxygen dissociation curve, what percentage of oxygen is released to the tissues when PO 2 averages 40 mm Hg? a. 75% c. 100% b. 25% d. 50% 5. What factors are known to influence platelet metabolism and function? a. Storage temperature c. Platelet count b. Initial pH d. All of the above 6. Which of the following red blood cell morphologies may be pres ent on the peripheral blood smear as a result of loss of RBC membrane? a. Spherocytes c. Burr cells b. Target cells d. Schistocytes 7. What does the term autologous transfusion refer to? a. A parent donating blood for his or her child b. An individual donating blood for a friend c. An individual donating blood for a relative d. An individual donating blood for his or her own transfusion 8. What is the primary function of hemoglobin? a. Iron metabolism c. Oxygen transport b. Porphyrin synthesis d. Signal transduction 9. All of the following areas of red blood cell biology are crucial for normal erythrocyte survival except: a. Cellular metabolism. c. Site of the ABO antigen attachment. b. RBC membrane. d. Hemoglobin structure. This study source was downloaded by 100000826342158 from CourseHero.com on 09 -15-2021 17:54:15 GMT -05:00 https://www.coursehero.com/file/25537437/ch01rtf/ 10. What is the correct biochemical composition of the RBC membrane? a. 52% protein, 40% lipid, 8% carbohydrate b. 40% protein, 8% lipid, 52% carbohydrate c. 8% protein, 52% lipid, 40% carbohydrate d. 8% lipid, 40% carbohydrate, 52% protein 11. All of the following biochemical changes are associated with loss of red blood cell viability upon storage except: a. Decreased pH. c. Increased ATP level. b. Loss of red blood cell function. d. Decreased glucose consumption. 12. Which red blood cell preservative has a storage time of 35 days? a. ACD c. AS-1 b. CPDA -1 d. CPD 13. The RBC membrane is relatively permeable to all of the following except: a. Chloride. c. Bicarbonate. b. Sodium. d. Water. 14. What percentage of platelets is sequestered in the spleen as functional reserve after being released from the bone marrow? a. 30% c. 10% b. 50% d. 25% 15. What is the major biochemical consideration in platelet storage? a. Glucose metabolism c. Production of carbon dioxide b. Oxygen supply d. Regulation of pH 16. What would the hemoglobin -oxygen dissociation curve depic t in a patient exhibiting clinical signs of alkalosis? a. Normal c. Shift to the right b. Shift to the left d. None of the above 17. Name the main lipid components of a red blood cell membrane. a. Phospholipid c. Glycolipid b. Sphingomyelin d. Glycophorin A 18. The ABO blood groups were discovered in 1901 by whom? a. Charles Drew c. Loutit and Mollison b. Karl Landsteiner d. Edward Lindeman 19. A standing order of platelets was shipped to your facility by your supplier. It was inadvertently left in the corner of the department until discovered 36 hours later. What would the appropriate action be for the blood banker? a. If the temperature in the box was 22 +/- 2°C and the platelet swirl seemed OK, it would be OK to accept the unit into inventory. b. The platelets have fallen outside the supplier’s quality assurance. The unit should be discarded because the pH has probably dropped too low and platelet activation has been compromised. c. If the temperature was 1°C to 6°C and the platelet swirl seemed OK, it would be OK to This study source was downloaded by 100000826342158 from CourseHero.com on 09 -15-2021 17:54:15 GMT -05:00 https://www.coursehero.com/file/25537437/ch01rtf/ accept the unit into inventory. d. If the platelets appeared OK and passed the platelet swirl test after being placed on the agitator, they could be accepted into the inventory. 20. Which metabolic pathway permits the accumulation of 2,3 diphosphoglycerate (2,3-DPG)? a. Glycolysis c. Pentose phosphate shunt b. Luebering -Rapoport shunt d. Methemoglobin reductase 21. All of the following are consistent with a "shift to the right" of the hemoglobin -oxygen dissociation curve except: a. Increased 2,3-DPG. b. 50% O2 saturation to tissues. c. Decreased 2,3-DPG. d. Decreased hemoglobin affinity for O2. 22. What is the normal platelet count range per cubic millimeter? a. 100 to 350 c. 50,000 to 200,000 b. 150,000 to 350,000 d. 350,000 to 500,000 23. What cryoprotective agent is added to red blood cells upon freezing? a. Dextrose c. Glycerol b. Adsol d. All of the above 24. If platelets are to be stored for 5 days on a rotator, what is the optimal storage temperature? a. 1°C to 6°C c. 35°C to 37°C b. 20°C to 24°C d. 1°C to 10°C 25. What role do platelets play in hemostasis? a. Maintenance of vascular integrity b. Initial arrest of bleeding by platelet plug formation c. Stabilization of the hemostatic plug d. All of the above 26. Which of the following best describes "integral" membrane proteins? a. Reside at the cytoplasmic surface of membrane b. Span the entire membrane surface c. Form the red blood cell cytoskeleton d. None of the above 27. How is stroma -free hemoglobin solution prepared? a. Outdated red blood cells are concentrated, and stroma is removed. b. Outdated red blood cells are diluted with saline, and stroma is removed. c. Outdated red blood cells are lysed, and stroma is removed. d. None of the above 28. What is the normal life span of an RBC? a. 100 days c. 120 hours b. 120 days d. 2 days 29. Regarding loss of RBC membrane deformability, all of the following are true except: a. Increase in ATP level. b. Decrease in ATP level.The benefits of buying summaries with Stuvia:
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